Suggested Citation:"Appendix A: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
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Appendix A
Workshop Agenda
Examining Special Nutritional Requirements in Disease States:
A Workshop
Planning Committee on Examining
Special Nutritional Requirements in Disease States
April 2–3, 2018
National Academy of Sciences Building
Lecture Room
2101 Constitution Avenue, NW
Washington, DC
Workshop Objectives
- Examine pathophysiological mechanisms by which specific diseases impact nutrient metabolism and nutrition status and whether this impact would result in nutrient requirements that differ from the Dietary Reference Intakes.
- Explore the role of genetic variation in nutrition requirements.
- Examine nutrient requirements in certain chronic conditions or acute phases for which emerging data suggest a contribution of nutrition status to disease outcomes. Consider the scientific evidence needed to establish such relationships and discuss principles about the relationship between nutrition requirements and specific diseases.
Suggested Citation:"Appendix A: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
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- Explore how a disease state impacts nutrient metabolism and nutritional status and, conversely, how nutritional status impacts the disease state.
- Identify promising approaches and challenges to establishing a framework for determining special nutrient requirements related to managing disease states.
WORKSHOP DAY 1: APRIL 2, 2018, 8:30 AM–5:15 PM
| 7:30–8:30 AM | Registration |
| Session 1: Introduction of the Concepts and Context of the Workshop | |
| Moderator: Barbara Schneeman, University of California, Davis | |
| 8:30 | Origins of the Workshop |
| Barbara Schneeman, University of California, Davis, Planning Committee Chair | |
| 8:50 | What Defines a Special Nutritional Requirement? |
| Patsy Brannon, Cornell University | |
| 9:10 | The Underlying Biological Processes of Special Nutritional Requirements |
| Patrick Stover, Texas A&M AgriLife | |
| 9:30 | Moderated Panel Discussion and Q&A |
| 10:00 | Break |
| Session 2: Addressing Nutrient Needs Due to Loss of Function in Genetic Diseases | |
| Moderator: Erin MacLeod, Children’s National Health System | |
| 10:20 | Understanding the Basis of Nutritional Needs in Phenylketonuria |
| Denise Ney, University of Wisconsin–Madison | |
| 10:40 | Nutritional Inadequacies in Mitochondrial-Associated Metabolic Disorders |
| Marni Falk, Children’s Hospital of Philadelphia (via Zoom) | |
| 11:00 | Contribution of Nutrients in Complex Inborn Errors of Metabolism: The Case of Methylmalonic Acidemia (MMA) |
| Charles Venditti, National Human Genome Research Institute, National Institutes of Health | |
Suggested Citation:"Appendix A: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
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| 11:20 | Lessons Learned: What We Know About Nutrition Management for Inborn Errors of Metabolism |
| Sue Berry, University of Minnesota | |
| 11:40 | Moderated Panel Discussion and Q&A |
| 12:00–1:00 PM | Lunch |
| Session 3: Disease-Induced Loss of Function and Tissue Regeneration | |
| Moderator: Alex Kemper, Nationwide Children’s Hospital | |
| 1:00 | Examples of Gastrointestinal Dysfunction and Malabsorption of Nutrients: Intestinal Failure |
| Chris Duggan, Boston Children’s Hospital (via Zoom) | |
| 1:30 | Examples of Gastrointestinal Dysfunction and Malabsorption of Nutrients: Cystic Fibrosis |
| Sarah Jane Schwarzenberg, University of Minnesota Masonic Children’s Hospital | |
| 1:50 | Nutritional Requirements for Inflammatory Bowel Disease |
| Dale Lee, Seattle Children’s Hospital | |
| 2:10 | Blood–Brain Barrier Dysfunction and Resulting Brain Nutrient Deficiencies |
| Martha Field, Cornell University | |
| 2:30 | Macro- and Micronutrient Homeostasis in the Setting of Chronic Kidney Disease |
| Alp Ikizler, Vanderbilt University | |
| 2:50 | Moderated Panel Discussion and Q&A |
| 3:15 | Break |
| Session 4: Disease-Induced Deficiency and Conditionally Essential Nutrients in Disease | |
| Moderator: Bernadette Marriott, Medical University of South Carolina | |
| 3:30 | Arginine as an Example of a Conditionally Essential Nutrient: Sickle Cell Anemia and Surgery |
| Claudia Morris, Emory University School of Medicine | |
Suggested Citation:"Appendix A: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×
| 3:50 | Nutritional Needs in Hypermetabolic States: Burns, Cachexia, and Surgery |
| Paul Wischmeyer, Duke University School of Medicine [NOTE: He did not speak at the workshop.] | |
| 4:10 | Traumatic Brain Injury: Pathophysiological Mechanisms and Potential Nutrient Needs |
| Angus Scrimgeour, U.S. Army Research Institute of Environmental Medicine | |
| 4:30 | Metabolic Turnover, Inflammation, and Redistribution: Impact on Nutrient Requirements |
| Jesse Gregory, University of Florida | |
| 4:50 | Moderated Panel Discussion and Q&A |
| 5:15 | Adjourn First Day |
WORKSHOP DAY 2: APRIL 3, 2018, 8:30 AM–1:00 PM
| 7:30–8:30 AM | Registration |
| Session 5: Building the Evidence Base: Research Approaches for Nutrients in Disease States | |
| Moderator: Alex Kemper, Nationwide Children’s Hospital | |
| 8:30 | Type and Strength of Evidence Needed for Determining Special Nutrient Requirements |
| Amanda MacFarlane, Health Canada | |
| 8:50 | Identification and Validation of Biomarkers in Disease States |
| Patrick Stover, Texas A&M AgriLife | |
| 9:10 | Innovative Causal Designs for Efficacy: What Type of Evidence Is Needed? |
| Nicholas Schork, J. Craig Venter Institute | |
| 9:30 | Examples of a Complex Disease |
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| Steve Clinton, The Ohio State University | |
| 10:15 | Moderated Panel Discussion and Q&A |
| 10:45 | Break |
Suggested Citation:"Appendix A: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×
| Session 6: Future Opportunities | |
| Moderator: Barbara Schneeman, University of California, Davis | |
| 11:00 | Principles Learned from Workshop Presentations |
| Barbara Schneeman, University of California, Davis | |
| 11:20 | Panel Discussion |
| Susan Barr, University of British Columbia Kristen D’Anci, ECRI Institute (via Zoom) Tim Morck, Spectrum Nutrition LLC Virginia A. Stallings, Children’s Hospital of Philadelphia |
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| 12:30 PM | Sponsor Remarks |
| Paul Coates, National Institutes of Health Patricia Hansen, U.S. Food and Drug Administration Caren Heller, Crohn’s & Colitis Foundation Chantal Martineau, Health Canada Sarah Ohlhorst, American Society for Nutrition Alison Steiber, Academy of Nutrition and Dietetics |
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| 1:00 | Meeting Adjourned |
Suggested Citation:"Appendix A: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
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