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Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop (2018)

Chapter: Appendix B: Speaker and Moderator Biographical Sketches

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Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
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Appendix B

Speaker and Moderator Biographical Sketches

Susan I. Barr, Ph.D., is Professor Emeritus of Food, Nutrition, and Health at the University of British Columbia. Her research interests relate to how women’s cognitions about food, eating, and body weight may have physiological implications for their health. She has also done work examining dietary practices and nutrient adequacy. Dr. Barr was involved in the development of the initial Dietary Reference Intakes (DRIs) as a member and Chair of the Subcommittee on Interpretation and Uses of DRIs, and subsequently served on the Committee on Development of Guiding Principles for the Inclusion of Chronic Disease Endpoints in Future Dietary Reference Intakes. She has also been a member of a number of Health Canada committees. Dr. Barr received her Ph.D. in human nutrition from the University of Minnesota and has received awards for teaching, research, and service.

Susan A. Berry, M.D., is Division Director for Genetics and Metabolism in the Department of Pediatrics at the University of Minnesota. She has been at the University of Minnesota since 1978, where she completed her residency in Pediatrics and was a fellow in Medical Genetics. She joined the staff of the Department in 1984 and is currently a Professor in the Departments of Pediatrics; Ophthalmology and Visual Neurosciences; and Genetics, Cell Biology, and Development. Dr. Berry’s research focuses on long-term follow-up for newborn-screened conditions. As a nationally recognized geneticist and expert in inborn errors of metabolism, Dr. Berry sees both child and adult patients for genetic consultation at the

Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
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University of Minnesota Physicians Pediatric Specialty Clinic. She also attends the Pediatric and Adult Metabolic Clinics, providing care for children and adults with inborn errors of metabolism. She also offers her expertise for inpatient consultation and care. Dr. Berry is a member of the Minnesota Department of Health Newborn Screening Advisory Committee, the Society for Inherited Metabolic Disorders, and the American Society of Human Genetics, and she is a Fellow of the American Academy of Pediatrics and of the American College of Medical Genetics. Dr. Berry received her M.D. from the University of Kansas.

Patsy M. Brannon, Ph.D., R.D., is a Professor in the Division of Nutritional Sciences at Cornell University, where she has also served as Dean of the College of Human Ecology. Before moving to Cornell University, Dr. Brannon was Chair of the Department of Nutrition and Food Science, University of Maryland. She has also served as Visiting Professor at the Office of Dietary Supplements of the National Institutes of Health. Her research focus includes nutritional and metabolic regulation of gene expression, especially as relating to human development, the placenta, and exocrine pancreas. She was a member of the National Academies of Sciences, Engineering, and Medicine’s Committee on Dietary Reference Intakes for Vitamin D and Calcium, and she is currently a member of the National Academies’ Food and Nutrition Board. Dr. Brannon is a member of a number of professional and scientific associations and has served on the Executive Board of the American Society for Nutrition. She has received numerous awards, including the Pew Faculty Scholar in Nutrition award as well as the Centennial Laureate award from Florida State University. Dr. Brannon received her Ph.D. from Cornell University in nutritional biochemistry.

Steven K. Clinton, M.D., Ph.D., is a Professor in the Department of Internal Medicine, Division of Medical Oncology at The Ohio State University. He is the Program Leader for the Molecular Carcinogenesis and Chemoprevention Program of the Comprehensive Cancer Center and serves the James Cancer Hospital as Director of Prostate and Genitourinary Oncology. Dr. Clinton is a faculty member of the campus-wide Ohio State University Nutrition Graduate Program and is Co-Director of the Center for Advanced Functional Foods Research and Entrepreneurship. His research examines fundamental mechanisms underlying the development of cancer and studies novel prevention and therapeutic strategies in human clinical trials. His cancer research interests within nutritional sciences include the roles of energy intake, bioactive lipids, vitamin D, carotenoids, and other phytochemicals. Dr. Clinton received his M.D. from the

Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×

University of Illinois College of Medicine and his Ph.D. in Nutritional Sciences from the University of Illinois at Urbana-Champaign.

Kristen E. D’Anci, Ph.D., has more than 20 years of experience conducting and reporting scientific research in the biomedical fields, including drug abuse and nutrition. As an Associate Director in ECRI Institute’s Evidence-based Practice Center (EPC) and Health Technology Assessment group, she performs and writes systematic reviews on topics such as medical treatments and behavioral health. Since joining ECRI, she has worked as Principal Investigator or Co-Investigator on clinical practice guidelines for the Department of Veterans Affairs/Department of Defense, the American College of Rheumatology, and an EPC report supporting upcoming guidelines from the National Institutes of Health’s National Heart, Lung, and Blood Institute. Before her work at ECRI Institute, Dr. D’Anci was an Assistant Professor of Biopsychology at Salem State University in Salem, Massachusetts, and a biobehavioral researcher at Tufts University in Medford, Massachusetts. She completed two postdoctoral programs, one in Clinical Nutrition at Tufts University and one in Behavioral Pharmacology at Harvard University, and earned her doctorate in Experimental Psychology from Tufts University. In addition to her work at ECRI, she currently serves as Associate Editor for the journal Nutrition Reviews and she is a member of both the GRADE (Grading of Recommendations Assessment, Development and Evaluation) Working Group and the Guidelines International Network.

Christopher Duggan, M.D., M.P.H., is a Professor in the Departments of Nutrition and Global Health and Population at the Harvard T.H. Chan School of Public Health. He is also Professor of Pediatrics at Harvard Medical School and Director of the Center for Nutrition at the Boston Children’s Hospital. His major research interests include the nutritional management of acute and persistent diarrhea, micronutrient trials in developing countries to prevent diarrhea and respiratory infections, the definition of biomarkers of environmental enteric dysfunction, and general aspects of energy and protein metabolism in catabolic diseases. He has completed studies in both developing and industrialized countries on the micronutrient status of children, including those with cystic fibrosis, malaria, undernutrition, and intestinal failure. Dr. Duggan has twice received the Physician Nutrition Specialist Award from the American Society of Nutrition, was the 2015 recipient of the Fomon Nutrition Award from the American Academy of Pediatrics, and has been a visiting professor in China, India, Tanzania, and many other countries. He received his M.D. from the Johns Hopkins University School of Medicine and his M.P.H. from the Harvard T.H. Chan School of Public Health.

Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×

Marni J. Falk, M.D., is Executive Director of the Mitochondrial Medicine Frontier Program at the Children’s Hospital of Philadelphia (CHOP) and Associate Professor in the Division of Human Genetics within the Department of Pediatrics at the University of Pennsylvania Perelman School of Medicine. She works to improve diagnostic approaches and genomic resources for mitochondrial disease, including organization of a global Mitochondrial Disease Sequence Data Resource consortium. Dr. Falk is also the Principal Investigator of a translational research laboratory group at CHOP that investigates the causes and global metabolic consequences of mitochondrial disease, as well as targeted therapies, in Caenorhabditis elegans, zebrafish, mouse, and human tissue models of genetic-based respiratory chain dysfunction. She also directs multiple clinical treatment trials in mitochondrial disease patients and she has authored more than 90 publications in the areas of human genetics and mitochondrial disease. Dr. Falk also directs the CHOP/University of Pennsylvania Mitochondria Research Affinity Group, which has 250 participants. She is Chair of the Scientific and Medical Advisory Board and serves on the Board of Trustees of the United Mitochondrial Disease Foundation. She is a founding member of the CHOP Center for Mitochondrial and Epigenomic Medicine and is the CHOP-site Principal Investigator of the North American Mitochondrial Disease Consortium. She is a member of the Mitochondrial Medicine Society, Society for Pediatric Research, Society for Inherited Metabolic Disease, American Society of Human Genetics, and American College of Medical Genetics and Genomics, and is an elected member of the University of Pennsylvania John Morgan Society, Interurban Clinical Club, and American Society of Clinical Investigators. Dr. Falk received her M.D. from the George Washington University School of Medicine.

Martha S. Field, Ph.D., is an Assistant Professor in the Division of Nutritional Sciences at Cornell University. Her research focuses on understanding the complexity of gene–gene, gene–nutrient, and gene–nutrient–environment interactions that affect cellular metabolism and on the biochemical mechanisms whereby perturbations in metabolism affect human health and disease. Impaired folate-dependent one-carbon metabolism is associated with adverse physiological outcomes that include certain cancers, cardiovascular disease, neurological impairments, and birth defects. Dr. Field uses several in vitro and in vivo model systems to study the mechanisms that underlie physiological outcomes associated with perturbed one-carbon metabolism. More specifically, she is interested in the contributions of folate nutrition and enzyme localization in supporting mitochondrial DNA precursor synthesis, with a focus on understanding how folate nutrition affects mitochondrial DNA integrity and pathogenesis of metabolic diseases such as mitochondrial DNA

Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×

depletion syndromes, chronic disease, and age-related decline in mitochondrial function. Recently, her research has focused on the metabolism of erythritol, which is a product of the pentose phosphate pathway and which has emerged as a biomarker of weight gain and adiposity in young adults. Dr. Field received her Ph.D. in biochemistry and molecular and cell biology from Cornell University.

Jesse F. Gregory, Ph.D., is a Professor of Food Science and Human Nutrition at the University of Florida. The focus of his research encompasses basic aspects of B vitamins in human nutrition and metabolism in health and disease. He has extensive research experience in mammalian vitamin metabolism, including folate and vitamin B6 analysis, chemistry, bioavailability, and metabolic function using in vivo studies with animal, cell, and human protocols. His research group has extensive experience with studies of folate and one-carbon metabolism, various global and targeted metabolomic methods, and stable isotopic tracer kinetic techniques to assess metabolic function and fluxes in humans. Dr. Gregory is Associate Editor of The Journal of Nutrition and was elected as a Fellow of the American Society for Nutrition in 2016. Dr. Gregory received his Ph.D. in food science and human nutrition from Michigan State University.

T. Alp Ikizler, M.D., is the Catherine McLaughlin Hakim Chair in Vascular Biology and Professor of Medicine at the Vanderbilt University School of Medicine (VUSM) in Nashville, Tennessee. He is Associate Director of the Division of Nephrology, a member of the American Society of Clinical Investigation (ASCI) and a member of ASCI Advocacy Committee. Dr. Ikizler’s clinical interests and expertise are focused on the care of patients with chronic kidney disease, end-stage renal disease on maintenance dialysis, and acute kidney injury. Dr. Ikizler was the Medical Director and Chief Executive Officer of the Vanderbilt University Medical Center Outpatient Dialysis unit between 2000 and 2012. He has significant research and clinical interest in nutritional and metabolic aspects of acute and chronic disease states. As a clinical investigator focused on mechanisms of disease and patient-related outcomes, he is the Principal Investigator of a number of ongoing studies aimed at improving the outcomes and quality of life in patient populations ranging from early kidney disease to patients on maintenance dialysis and patients with acute kidney injury. He is currently an Associate Editor for Kidney International and is Co-Editor of the Handbook of Nutrition in Kidney Disease. Previously he served as President of the International Society of Renal Nutrition and Metabolism, Associate Editor of the Journal of the American Society of Nephrology, Director of the Master of Science in Clinical Investigation Program at VUSM, and member and Chair of the American Board of Internal Medicine Nephrology

Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×

Test Writing Committee. He is the recipient of National Kidney Foundation Joel Kopple Award and the International Society of Renal Nutrition and Metabolism Thomas Addis Award. He has published more than 280 original articles, 50 editorial reviews, and 20 book chapters. Dr. Ikizler received his M.D. from the Istanbul University Faculty of Medicine.

Alex R. Kemper, M.D., is a board-certified pediatrician and Chief of the Division of Ambulatory Pediatrics at the Nationwide Children’s Hospital, Columbus, Ohio. Dr. Kemper’s clinical and research interests include improving the quality of care that children receive by strengthening the linkages between primary care, specialty care, and public health services. He has studied a wide array of preventive services, including the prevention of amblyopia, the early detection and treatment of lead poisoning, and newborn screening. Dr. Kemper joined the U.S. Preventive Services Task Force in January 2014. Dr. Kemper is Deputy Editor of Pediatrics, the leading journal in the nation covering issues of child health. He is also a member of many organizations and societies, including the American Academy of Pediatrics, the Academic Pediatric Association, the American Pediatric Society, and the Society for Pediatric Research. He directs the Condition Review Workgroup for the Secretary of Health and Human Services’ Advisory Committee on Heritable Disorders in Newborns and Children, which makes evidence-based recommendations about conditions that should be recommended for inclusion in State newborn screening panels. Dr. Kemper also works with Bright Futures to develop an evidence-based process of making recommendations for services that should be included as part of routine pediatric preventive care. Dr. Kemper received a B.S.E. from Johns Hopkins University. He completed an M.P.H. in epidemiology and an M.S. in biomedical engineering, focusing on medical informatics, at the University of North Carolina. Dr. Kemper earned his M.D. from the Duke University Medical School, where he completed a pediatric internship and residency. He also completed a fellowship in health services research and a preventive medicine residency at the University of North Carolina.

Dale Lee, M.D., is an Assistant Professor of Pediatrics at the Seattle Children’s Hospital at the University of Washington. He is the Chair of the Hospital Nutrition Committee and Director of the Celiac Disease Program. Dr. Lee is dual fellowship trained in Pediatric Gastroenterology and Nutrition from the Children’s Hospital of Philadelphia and the University of Pennsylvania. In addition, he is trained in clinical epidemiology. Dr. Lee is an organizer for a multidisciplinary symposium on a “Food Systems Approach to Gut Health” with the Department of Food Science at The Pennsylvania State University. He is a current scholar in the Clinical

Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×

Research Scholar’s Program at the Seattle Children’s Hospital studying dietary therapy for inflammatory bowel disease (IBD) as well as studying the role of dietary exposures in IBD pathogenesis. Dr. Lee’s research program incorporates a multidisciplinary approach, including clinical gastroenterology, clinical nutrition, food science, plant science, and nutrition epidemiology. Dr. Lee received his M.S. in clinical epidemiology from the University of Pennsylvania and his M.D. from The University of Texas Southwestern Medical School.

Amanda MacFarlane, Ph.D., is a Research Scientist and Head of the Micronutrient Research Section in the Nutrition Research Division at Health Canada. She is an Adjunct Professor in the Department of Biochemistry, Microbiology, and Immunology at the University of Ottawa and the Department of Biology at Carleton University. She received her Ph.D. in Biochemistry in 2004 at the University of Ottawa, for which she won the 2003 Ron Oelbaum Award for an Outstanding Canadian Research Scientist younger than age 35 years from the Juvenile Diabetes Research Foundation. She did her postdoctoral research with Dr. Patrick Stover at Cornell University, where she examined the effect of altered folate metabolism on genome stability and gene expression in models of colon cancer. She joined Health Canada in 2008 where she examines the impact of maternal and paternal folate intake on germline genomic and epigenomic stability, and its effect on offspring health and disease. She also uses national health survey data to identify the socioeconomic, dietary, and genetic determinants of folate and B vitamin status of Canadians. She is the Canadian lead and Chair of the Joint Canada–U.S. Dietary Reference Intakes Working Group. She was the Project Co-Director for the expert panel and workshop “Options for Addressing Consideration of Chronic Disease Endpoints for Dietary Reference Intakes (DRIs).”

Erin MacLeod, Ph.D., is Director of Metabolic Nutrition in the Division of Genetics and Metabolism at the Children’s National Health System in Washington, DC. In her current position Dr. MacLeod is part of an experienced clinical team that manages more than 400 patients with inborn errors of metabolism and participates in a variety of clinical research projects. Her primary research focus has been the nutritional management of phenylketonuria (PKU). She participated in the clinical trials for glycomacropeptide and conducted a study to examine the change in phenylalanine tolerance in adults with PKU. She received her Ph.D. from the University of Wisconsin–Madison.

Bernadette Marriott, Ph.D., holds the positions of Professor, Division of Gastroenterology and Hepatology, Department of Medicine, and Profes-

Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×

sor, Military Division, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina. Dr. Marriott has 40 years of experience in the fields of nutrition, psychology, and comparative medicine with expertise in diet, nutrition, and chronic disease. Dr. Marriott has worked in scientific settings in the federal government, universities, and foundations. Former positions include founding Director of the Office of Dietary Supplements, National Institutes of Health (NIH); Associate Director, the National Academies’ Food and Nutrition Board; Vice President, Research Triangle Institute International; and Research Vice Provost and Graduate Dean, Northern Arizona University. Her research has focused on clinical trials and nutritional epidemiology studies involving diet and health. She is currently leading or has recently led research projects funded by the U.S. Army, Department of Defense, NIH, U.S. Department of Agriculture, industry, and foundations. Ongoing and recent research has assessed the use of added sugar and sugar-sweetened beverages in the United States and the impact of fatty acid supplementation on cognitive performance under stress and measures of mental health status among military personnel and veterans and nonveterans at risk of suicide. She has published extensively, has been on a number of national committees, and university and nonprofit scientific advisory boards, and is a frequent speaker on diet, dietary supplements, and health. Dr. Marriott is currently a member of the National Academies’ Food and Nutrition Board and was elected a Fellow of the American Society for Nutrition in 2016. She has a B.Sc. in biology/immunology from Bucknell University, a Ph.D. in psychology from King’s College, University of Aberdeen, Scotland, and postgraduate training in trace mineral nutrition, comparative medicine, and advanced statistics.

Timothy A. Morck, Ph.D., is the Founder and President of Spectrum Nutrition, LLC, a consulting firm that provides expertise in nutrition-related basic/clinical research, product development, regulatory and public policy, and global scientific affairs. Dr. Morck’s career includes clinical nutrition practice, research, and medical school faculty appointments (University of Kansas Medical Center; Eastern Virginia Medical School; and Veterans Affairs Medical Center, Hampton, Virginia), scientific association management (International Life Sciences Institute [ILSI]-North America), entrepreneurial personalized nutrition start-ups (MenuDirect Corp. and DSM Personalized Nutrition), and executive and senior management positions at several global food, nutrition, and pharmaceutical companies, including The Dannon Company, Mead Johnson Nutritionals, Abbott Nutrition, Nestlé Health Science, and Nestlé Corporate Affairs. His unique multidisciplinary perspective integrates scientific affairs and marketing to achieve business objectives, with a passion for personalized approaches that improve nutrition, health, and wellness for individuals,

Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×

patients, and society. The interplay between the legal, scientific, and regulatory framework surrounding medical foods has been a particular focus for him. He received M.S. and Ph.D. degrees in nutrition (biochemistry and physiology minors) from Cornell University.

Claudia R. Morris, M.D., FAAP, is an Associate Professor of Pediatrics and Emergency Medicine at the Emory University School of Medicine. She is also a pediatric emergency medicine attending physician at Children’s Healthcare of Atlanta. Dr. Morris has been involved in sickle cell disease (SCD) research for more than 20 years, has a history of the National Institutes of Health and the U.S. Food and Drug Administration/R01 and industry-sponsored funding, and has led several single and multi-center trials. She has a special interest in translational research that targets inflammation and oxidative stress. From the start of her career, Dr. Morris’s research endeavors have focused on nutritional interventions based on specific metabolic pathways that cross disease disciplines, identifying alterations in the arginine metabolome in SCD, thalassemia, asthma, and pulmonary hypertension. She also published the first randomized, blinded, placebo-controlled trial of arginine therapy to treat pain in children with SCD. Dr. Morris’s efforts have always encompassed an integrative approach to the practice of medicine. She is a firm believer in nutrition as medicine, and appreciates the growing need to address distinctive nutritional requirements provoked by some acute and chronic illnesses, with SCD as an ideal paradigm. Dr. Morris received her M.D. from Eastern Virginia Medical School.

Denise Ney, Ph.D., is a Professor of Nutritional Sciences and Affiliate Faculty Waisman Center, University of Wisconsin–Madison. Throughout her 30-year career as a faculty member at the University of Wisconsin–Madison, Dr. Ney has used surgical and genetic animal models where dietary manipulation was a primary variable to test a specific hypothesis. This research has resulted in translation of her research findings to humans for the treatment of short bowel syndrome and since 2003, the genetic disorder phenylketonuria (PKU). Her current research program to improve the nutritional management of PKU has resulted in a new paradigm for the PKU diet using glycomacropeptide medical foods. Dr. Ney is the 2015 recipient of the Mary Swartz Rose Senior Investigator Award from the American Society for Nutrition. She received her Ph.D. in nutrition sciences from the University of California, Davis.

Barbara O. Schneeman, Ph.D., served as the Higher Education Coordinator at the U.S. Agency for International Development from 2015–2016. From 2004 to 2013 she was the Director of the Office of Nutrition, Label-

Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×

ing, and Dietary Supplements at the U.S. Food and Drug Administration (FDA). In that position, she oversaw the development of policy and regulations for dietary supplements, labeling, food standards, infant formula, and medical foods and served as U.S. delegate to two Codex committees (Food Labeling and Nutrition and Foods for Special Dietary Uses). From 1976–2004, she was a member of the nutrition faculty at the University of California, Davis (UC Davis), and is currently emerita professor of nutrition. At UC Davis she served in several administrative roles, including Chair of the Department of Nutrition, Dean of the College of Agricultural and Environmental Sciences, and Associate Vice Provost for University Outreach. She has been a visiting scientist at the University of California, San Francisco, and Assistant Administrator for Nutrition in the Agricultural Research Service of the U.S. Department of Agriculture (USDA). Professional activities include participation in Dietary Guidelines Advisory Committees; being a past member of the National Academies’ Food and Nutrition Board; and serving as a member of committees for the National Academies, USDA, the Food and Agriculture Organization, the World Health Organization, the American Society for Nutrition, and the Institute of Food Technologists. She has been Associate Editor for the Journal of Nutrition and on several editorial boards, including Nutrition Reviews, Journal of Nutrition, and Journal of Food Science. Her professional honors include Fellow of the American Society of Nutrition, Fellow of the American Association for the Advancement of Science, the Carl Fellers Award from the Institute of Food Technologists, the FDA Commissioner’s Special Citation and the Harvey W. Wiley Medal, the FDA Merit Award, the Samuel Cate Prescott Award for research, Future Leader Award, and several honorary lectureships. She is recognized for her work on dietary fiber, gastrointestinal function, development and use of food-based dietary guidelines, and policy development in food and nutrition. She received her Ph.D. in nutrition from the University of California, Berkeley.

Nicholas J. Schork, Ph.D., is Distinguished Professor of Quantitative Medicine at the Translational Genomics Research Institute in Phoenix, Arizona; Professor and Director of Human Biology at the J. Craig Venter Institute (JCVI) in La Jolla, California; and an Adjunct Professor of Psychiatry and Family Medicine and Public Health (Division of Bio-statistics) at the University of California, San Diego, in La Jolla, California. Before joining JCVI, Dr. Schork held faculty positions at The Scripps Research Institute, the Scripps Translational Science Institute, and Case Western Reserve University. Dr. Schork’s interests and expertise are in quantitative human biomedical science and integrated approaches to complex biological and medical problems. He has published more than 500 scientific articles and book chapters that consider novel data analysis

Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×

methodology, study designs, and applications. He has also mentored more than 75 graduate student and postdoctoral fellows, has 8 patents, and has helped establish 10 different companies in the biomedical science and applications. A member of several scientific journal editorial boards, Dr. Schork is a frequent participant in National Institutes of Health (NIH)related steering committees and review boards. He is director of the quantitative components of a number of national research consortia, including the NIH-sponsored Longevity Consortium and the National Institute of Mental Health–sponsored Bipolar Consortium. Dr. Schork earned his M.A. in philosophy, M.A. in statistics, and Ph.D. in epidemiology from the University of Michigan, Ann Arbor.

Sarah Jane Schwarzenberg, M.D., is currently an Associate Professor in the Department of Pediatrics and the Chief of Pediatric Gastroenterology, Hepatology, and Nutrition at the University of Minnesota Masonic Children’s Hospital. Dr. Schwarzenberg’s initial research was in the area of hepatic gene regulation during inflammation. She now focuses on clinical research in cystic fibrosis–associated gastrointestinal disease and nutrition and in chronic pancreatitis in childhood. She is a member of the Committee on Nutrition of the American Academy of Pediatrics. Dr. Schwarzenberg is the 2017 recipient of the Murray Davidson Award from the American Academy of Pediatrics Section on Gastroenterology, Hepatology, and Nutrition. She received her M.D. from the University of Tennessee Medical School.

Angus Scrimgeour, Ph.D., is a nutritional biochemist in the Military Nutrition Division at the U.S. Army Research Institute of Environmental Medicine, in Natick, Massachusetts. He received his M.Sc. in physiology and sports medicine from the University of Cape Town, South Africa, and his Ph.D. in cell and molecular biology from the University of Vermont. He has more than 15 years of experience developing animal models of human disease to validate nutritional countermeasures. Mild traumatic brain injury (mTBI) has become the signature injury in the current war(s) and to address this problem, Dr. Scrimgeour has developed nutritional interventions that increase resiliency to neurotrauma in animal models. Initial efforts have involved working with the Royal Dutch Military, studying the effects of explosive blast in rats on marginally zinc-deficient diets, and reporting on the cognitive deficits associated with mild-to-moderate TBI. Current research efforts use both blast and non-blast models to induce mTBI in rats, and then using anti-inflammatory, neuroprotectant food-supplements (containing omega-3, vitamin D, and/or zinc) to increase resiliency to the effects of neurotrauma. In 2017, this work effort was expanded to use similar diets in pre-clinical models of posttraumatic stress disorder.

Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×

Virginia A. Stallings, M.D., is the Jean A. Cortner Endowed Chair in Pediatric Gastroenterology, Professor of Pediatrics and Nutrition, and Director of the Nutrition Center at the Children’s Hospital of Philadelphia. Her research interests include pediatric nutrition, evaluation of dietary intake and energy expenditure, and nutrition-related chronic disease. Dr. Stallings has served on several National Academies committees, including the Committee on Food Allergies: Global Burden, Causes, Treatment, Prevention, and Public Policy; the Committee on Nutrition Standards for National School Lunch and Breakfast Programs; the Committee on Nutrition Services for Medicare Beneficiaries; the Committee on the Scientific Basis for Dietary Risk Eligibility Criteria for WIC (Special Supplemental Nutrition Program for Women, Infants, and Children) Programs; the Committee to Review the WIC Food Packages; and the Committee to Review Child and Adult Care Food Program Meal Requirements. She is a former member and Co-Vice Chair (2000–2002) of the National Academies’ Food and Nutrition Board. Dr. Stallings is board certified in pediatrics and clinical nutrition. She received the Fomon Nutrition Award from the American Academy of Pediatrics. Dr. Stallings earned an M.S. in human nutrition and biochemistry from Cornell University and an M.D. from the University of Alabama at Birmingham School of Medicine. She is a member of the National Academy of Medicine.

Patrick J. Stover, Ph.D., is Vice Chancellor and Dean for Agriculture and Life Sciences at Texas A&M AgriLife. He previously served as the Director of the Division of Nutritional Sciences at Cornell University. He is also Director of the World Health Organization Collaborating Centre on Implementation Research in Nutrition and Global Policy at Cornell University and past President of the American Society for Nutritional Sciences. Dr. Stover’s research interests focus on the biochemical, genetic, and epigenetic mechanisms that underlie the relationships between folic acid and human pathologies, including neural tube defects and other developmental anomalies, cardiovascular disease, and cancer. Specific interests include the regulation of folate-mediated one-carbon metabolism and cellular methylation reactions, molecular basis of the fetal origins hypothesis, development of mouse models to elucidate mechanisms of folate-related pathologies, and nuclear one-carbon metabolism. In 2016, he was elected as a member of the National Academy of Sciences, and in 2014 was elected as a Fellow of the American Association for the Advancement of Science. In 2014, he received the State University of New York Chancellor’s Award for Excellence in Scholarship and Creative Activities, the Osborne and Mendel Award for outstanding recent basic research accomplishments in nutrition from the American Society for Nutrition, and a MERIT award from the National Institute of Diabetes and

Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×

Digestive and Kidney Diseases. In 1996, he received the Presidential Early Career Award for Scientists and Engineers, the highest honor bestowed by the U.S. government on outstanding scientists and engineers beginning their independent careers. He has been selected as an Outstanding Educator four times by Cornell Merrill Presidential Scholars. Dr. Stover served two terms on the National Academies’ Food and Nutrition Board and he served on the Board’s Nutrigenomics Workshop Planning Group. Dr. Stover received his Ph.D. in biochemistry and molecular biophysics from the Medical College of Virginia.

David L. Suskind, M.D., is a Professor of Pediatrics in the Division of Gastroenterology at the University of Washington in Seattle. He is a pediatric gastroenterologist working within a tertiary care center at Seattle Children’s Hospital. His research has focused on the effect of the fecal microbial transplant and diet on inflammatory bowel disease (IBD), both of which affect the fecal microbiome. Dr. Suskind has conducted studies on the clinical, laboratory, and microbiome changes that occur after fecal microbial transplantation as well as on nutritional treatment approaches in IBD. His research on the specific carbohydrate diet in IBD has shown that patients with active Crohn’s disease and ulcerative colitis can go into clinical and biochemical remission with diet alone. His studies also examine the impact of diet on fecal microbiome composition. Clinically, he has focused his work within the Seattle Children’s Hospital IBD center, where his mission is to improve the quality of care and clinical outcomes for patients with IBD by focusing on the patient and not just their disease. Dr. Suskind received his M.D. from the Louisiana State University Medical School.

Charles P. Venditti, M.D., Ph.D., is Head of the Organic Acid Research Section and Senior Investigator of the National Human Genome Research Institute at the National Institutes of Health (NIH). He is also an attending physician at the Mark O. Hatfield Clinical Center at NIH, where he has initiated a translational research program to study the natural history and clinical phenotype(s) of the hereditary methylmalonic acidemias (MMA) and cobalamin metabolic disorders. The clinical research studies are paralleled by laboratory investigations that have focused on the development of experimental systems to study the genetics, genomics, and biochemistry of organic acid metabolism in model organisms, including roundworms, mice, and zebrafish. Using a translational research approach, Dr. Venditti and his colleagues have published a number of papers that connect disease pathophysiology in MMA to mitochondrial dysfunction and prove the efficacy of gene therapy as a treatment for both MMA and propionic acidemia. Dr. Venditti

Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×

was the 2009 recipient of a Presidential Early Career Award for Scientists and Engineers. Other awards include selection as an Outstanding New Investigator from the American Society of Gene and Cell Therapy in 2010 and election into the American Society of Clinical Investigation in 2012. Dr. Venditti received his M.D. and Ph.D. from The Pennsylvania State University.

Gary D. Wu, M.D., is the inaugural Ferdinand G. Weisbrod Professor in Gastroenterology at the Perelman School of Medicine, University of Pennsylvania. He is the Associate Chief for Research in the Division of Gastroenterology; Co-Director of the Penn-Children’s Hospital of Philadelphia (CHOP) Microbiome Program; Associate Director of the Joint Penn-CHOP Center for Digestive, Liver, and Pancreatic Medicine; and the Associate Director of the Center for Molecular Studies in Digestive and Liver Disease in which he is the Director of its Molecular Biology Core. As a physician-scientist, Dr. Wu’s laboratory focuses primarily on multidisciplinary team research in the gut microbiome to translate basic research at the wet bench into the clinical setting. Dr. Wu’s research into the gut microbiome began nearly a decade ago with projects focused on the impact of diet on the composition of the gut microbiota initially funded by the National Institutes of Health’s (NIH’s) Human Microbiome Project. Dr. Wu co-directs a number of NIH-funded projects, including a study examining the association of the gut microbiome with its metabolome and their correlations with the development of rapid growth and childhood obesity in a large longitudinal prospective cohort of children as well as the effects of chronic kidney disease on the gut microbiome and its metabolome. Dr. Wu’s laboratory is also investigating the co-metabolism of ammonia between the host and its microbiome through the hydrolysis of host urea by gut microbiota urease activity. To translate this technology into the clinical arena, he is leading a collaboration among the University of Pennsylvania, CHOP, and an industry partner, in a multidisciplinary effort to develop a microbiota-based therapy for patients with inborn errors of metabolism. Dr. Wu received his M.D. from Northwestern University Medical School.

Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×
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Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×
Page 120
Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×
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Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×
Page 122
Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×
Page 123
Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×
Page 124
Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×
Page 125
Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×
Page 126
Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×
Page 127
Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×
Page 128
Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×
Page 129
Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×
Page 130
Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×
Page 131
Suggested Citation:"Appendix B: Speaker and Moderator Biographical Sketches." National Academies of Sciences, Engineering, and Medicine. 2018. Examining Special Nutritional Requirements in Disease States: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25164.
×
Page 132
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The amount of nutrients required by an individual is determined by a number of physiological processes, including absorption, metabolism, stability, and bio-activation. These processes determine nutrient needs and provide variations in requirements in the population. All have modifiers and sensitizers, such as sex, genetics, pregnancy, age, pharmaceuticals, toxins, food matrix, and epigenetics. Disease can also be a major modifier of these processes. In April 2018, the National Academies of Science, Engineering and Medicine convened a workshop in order to explore the evidence for special nutritional requirements in disease states and the medical conditions that cannot be met with a normal diet. Participants explored the impact a disease state can have on nutrient metabolism and nutritional status, and attempted to close informational gaps. This publication summarizes the presentations and discussions from the workshop.

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