Part IV of this report offers this committee’s perspective on knowledge gaps it revealed through its review of the evidence. This part of the report consists of one chapter.
Chapter 12 synthesizes the committee’s assessment of the evidence to identify where research gaps exist related to the understanding of potassium and sodium intake levels that are adequate, are toxic, and reduce chronic disease risk. The committee also describes its experience of undertaking a Dietary Reference Intake (DRI) study that incorporated recommendations from the 2017 National Academies report Guiding Principles for Developing Dietary Reference Intakes Based on Chronic Disease and used an externally prepared systematic evidence review. Based on its experience, the committee highlights opportunities to enhance the DRI process.