Part I of this report presents background information about the study and a description of the methodological considerations reviewed by the committee in its approach to establish Dietary Reference Intakes (DRIs) for potassium and sodium. This part of the report consists of three chapters.
Chapter 1 provides context for the study. The chapter includes an introduction to the DRIs, the DRI organizing framework, and the Agency for Healthcare Research and Quality systematic review, Sodium and Potassium Intake: Effects on Chronic Disease Outcomes and Risks. The chapter also presents the Statement of Task for this study and a brief overview of the committee’s approach to its task.
Chapter 2 presents an overview of how the committee applied guidance from the 2017 National Academies of Sciences, Engineering, and Medicine report Guiding Principles for Developing Dietary Reference Intakes Based on Chronic Disease to its derivation of DRIs based on chronic disease.
Chapter 3 presents the methodological considerations related to assessing the evidence on potassium and sodium intake. The chapter discusses the application of the evidence to the decisions that informed the committee’s approach to establishing DRIs for potassium and sodium.