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Part I Defining and Measuring the U.S. Bioeconomy The first part of this report is focused on defining the U.S. bioeconomy; exploring the methods, data, and analysis needed to measure its value; and understanding how to determine the U.S. leadership position within the global bioeconomy. Chapter 2 examines the various conceptual approaches used around the world to understand and define the term âbioeconomy.â The committee characterizes the various bioeconomy definitions into three different visions: a biotechnology vision, a bioresource vision, and a bioecology vision. With this context, the chapter then refocuses on the committeeâs new definition, a comprehensive and flexible one that allows for future developments, and uses it to articulate the bounds of the U.S. bioeconomy. This discussion directly addresses the element of the committeeâs Statement of Task requesting that the committee âoutline the landscape of the U.S. bioeconomy.â Chapter 3 undertakes a detailed discussion of how to measure the value of the U.S. bioeconomy, responding directly to the first two bullets of the Statement of Task. First, the chapter examines the characteristics of the bioeconomy that set it apart from other sectors. Then, the chapter considers approaches for both identifying intangible assets and determining the value of the U.S. bioeconomy, in accordance with the committeeâs definition. This discussion culminates in a pilot valuation experiment that applies the valuation framework set forth in this chapter using the available data, while pointing out the data elements that are missing or difficult to parse out in a way that is specific to the bioeconomy. This discussion demonstrates a need for new data collection and analysis capabilities. Lastly, the chapter examines the trends and direction of the bioeconomy by analyzing national and private investments in research and development, as well as innovation outcomes from the bioeconomy. Chapter 4 then examines areas of U.S. leadership in the context of the global bioeconomy. To this end, the committee compares government investments, scientific output metrics, scientific training, and private innovation inputs. These four chapters set the foundation for the remainder of the report by articulating the scope, size, and value of the U.S. bioeconomy, while providing a rationale for how to determine those endpoints. 26 Prepublication Copy