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Next Steps for Functional Genomics: Proceedings of a Workshop (2020)

Chapter: Appendix B: Workshop Agenda

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Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2020. Next Steps for Functional Genomics: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25780.
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Appendix B

Workshop Agenda

Next Steps for Functional Genomics: A Workshop
February 10–12, 2020
National Academy of Sciences, Room 120
2101 Constitution Avenue, NW, Washington, DC 20418

DAY 1: MONDAY, FEBRUARY 10

8:45 Welcome and Opening Remarks
Steven Moss, National Academies of Sciences, Engineering, and Medicine
Donal Manahan, National Science Foundation
Gene Robinson, University of Illinois at Urbana-Champaign, Chair of the Steering Committee
9:00 Keynote Speaker
Introduced by Gene Robinson, University of Illinois at Urbana-Champaign
Design for Inference in Biology
Aviv Regev, Broad Institute and Massachusetts Institute of Technology
10:00–10:15 Coffee Break
10:15 Talks and Facilitated Panel Discussion: Case Studies on Building Functional Genomics Tools in Diverse Systems
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2020. Next Steps for Functional Genomics: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25780.
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  15-minute talks from each person followed by panel guided questions and discussion
Moderator: Lauren O’Connell, Stanford University
Andrea Sweigart, University of Georgia
Rachel Dutton, University of California, San Diego
Zoe Donaldson, University of Colorado Boulder
Dominique Bergmann, Stanford University
Steven Henikoff, Fred Hutchinson Cancer Research Center
12:00–1:00 Lunch
1:00 Facilitated Panel Discussion: Determining and Defining “Model” Systems for Diverse Functional Genomics Applications
10-minute introduction to topic from Paul Katz followed by a facilitated discussion
Moderator: Andrea Sweigart, University of Georgia
Paul Katz, University of Massachusetts Amherst
Lauren O’Connell, Stanford University
Zoe Donaldson, University of Colorado Boulder
Dominique Bergmann, Stanford University
2:15 Talks and Facilitated Panel Discussion: Understanding the Contributions of the Non-Protein-Coding DNA to Phenotype
15-minute talks from each person followed by panel-guided questions and discussion
Moderator: Terry Magnuson, University of North Carolina at Chapel Hill
Felicity Jones, Friedrich Miescher Laboratory of the Max Planck Society
Scott Edwards, Harvard University
Francois Spitz, The University of Chicago
3:45–4:00 Coffee/Snack Break
4:00 Facilitated Panel Discussion: Societal and Ethical Implications of Functional Genomics Research
5 minutes of opening comments by each panelist, followed by a facilitated discussion
Moderator: Zoe Donaldson, University of Colorado Boulder
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2020. Next Steps for Functional Genomics: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25780.
×
  Rebecca Walker, University of North Carolina at Chapel Hill
Scott Jackson, Bayer Crop Science
Ronald Sandler, Northeastern University
5:00 Closing Remarks
Philip Benfey, Duke University
5:00 Adjourn

DAY 2: TUESDAY, FEBRUARY 11

9:00 Keynote Speaker
Introduced by Trudy Mackay, Clemson University
Predicting Current and Future Sources of Variation in Quantitative Traits
Patricia Wittkopp, University of Michigan
10:00–10:15 Coffee Break
10:15 Talks and Facilitated Panel Discussion: Advancement of Research on Environmental Regulation of Gene Function
15-minute talks from each person followed by panel-guided questions and discussion
Moderator: Philip Benfey, Duke University
Sarah Kocher, Princeton University
Joanna Kelley, Washington State University
Nathan Springer, University of Minnesota
Trudy Mackay, Clemson University
12:00–1:00 Lunch
1:00 Talks and Facilitated Panel Discussion: Challenges and Successes of Integrating Large Datasets
15-minute talks from each person followed by panel-guided questions and discussion
Moderator: Norbert Tavares, Chan Zuckerberg Initiative
Alexis Battle, Johns Hopkins University
Saurabh Sinha, University of Illinois at Urbana-Champaign
Rahul Satija, New York Genome Center
Charles Danko, Cornell University
Genevieve Haliburton, Chan Zuckerberg Initiative
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2020. Next Steps for Functional Genomics: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25780.
×
2:20 Facilitated Panel Discussion: Pros and Cons of Consortia and Large Databases
2–3 minutes of opening comments by each panelist, followed by a facilitated discussion
Moderator: Charles Danko, Cornell University
Felicity Jones, Friedrich Miescher Laboratory of the Max Planck Society
Alexis Battle, Johns Hopkins University
Saurabh Sinha, University of Illinois at Urbana-Champaign
Rahul Satija, New York Genome Center
Sean Hanlon, National Cancer Institute, National Institutes of Health
3:15–3:30 Coffee/Snack Break
3:30 Interactive Session and Panel Discussion: Addressing Challenges in Education and Training
Groups of 6–8 will discuss prompt questions from 3:15–3:45. Each group will have 3–5 minutes to summarize its main points. We will then move into a panel discussion.
Moderator: Patricia Wittkopp, University of Michigan
Terry Magnuson, University of North Carolina at Chapel Hill
Arnaud Martin, The George Washington University
Lauren O’Connell, Stanford University
Grace Anderson, Octant
Rebecca Walker, University of North Carolina at Chapel Hill
5:00 Closing Remarks
Emma Farley, University of California, San Diego
5:05 Adjourn

DAY 3: WEDNESDAY, FEBRUARY 12

9:00 Talks and Facilitated Panel Discussion: Interpreting and Validating Results from High-Throughput Screening Approaches
15-minute talks from each person followed by panel-guided questions and discussion
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2020. Next Steps for Functional Genomics: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25780.
×
  Moderator: Trudy Mackay, Clemson University
David C. Page, Whitehead Institute
Emma Farley, University of California, San Diego
Philip Benfey, Duke University
Grace Anderson, Octant
Gary Churchill, The Jackson Laboratory
10:45 Interactive Session on the Future of Functional Genomics Research Goals
Participants will get into groups of 6–8 to think about the prompt questions related to short- and medium-term research goals of functional genomics. These groups will discuss from 10:40–11:20, followed by 5 minutes of reporting from each group on the main points it came up with. This will end with a larger discussion by all attendees.
Moderator: Emma Farley, University of California, San Diego
11:45 Future of Functional Genomics Town Hall
This is a final opportunity for any attendee to emphasize a point they heard during the meeting or bring up something that has not been addressed. Possible prompt questions will be provided.
Moderator: Gene Robinson, University of Illinois at Urbana-Champaign, Chair of the Steering Committee
12:25 Closing Remarks
Gene Robinson, University of Illinois at Urbana-Champaign, Chair of the Steering Committee
12:30 Meeting Adjourn
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2020. Next Steps for Functional Genomics: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25780.
×

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Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2020. Next Steps for Functional Genomics: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25780.
×
Page 165
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2020. Next Steps for Functional Genomics: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25780.
×
Page 166
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2020. Next Steps for Functional Genomics: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25780.
×
Page 167
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2020. Next Steps for Functional Genomics: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25780.
×
Page 168
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2020. Next Steps for Functional Genomics: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25780.
×
Page 169
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2020. Next Steps for Functional Genomics: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25780.
×
Page 170
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One of the holy grails in biology is the ability to predict functional characteristics from an organism's genetic sequence. Despite decades of research since the first sequencing of an organism in 1995, scientists still do not understand exactly how the information in genes is converted into an organism's phenotype, its physical characteristics. Functional genomics attempts to make use of the vast wealth of data from "-omics" screens and projects to describe gene and protein functions and interactions. A February 2020 workshop was held to determine research needs to advance the field of functional genomics over the next 10-20 years. Speakers and participants discussed goals, strategies, and technical needs to allow functional genomics to contribute to the advancement of basic knowledge and its applications that would benefit society. This publication summarizes the presentations and discussions from the workshop.

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