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Suggested Citation:"Appendix C: Open Session Agendas." National Academies of Sciences, Engineering, and Medicine. 2022. Review of U.S. EPA's ORD Staff Handbook for Developing IRIS Assessments: 2020 Version. Washington, DC: The National Academies Press. doi: 10.17226/26289.
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Appendix C

Open Session Agendas

February 11, 2021
Web Meeting

11:00 AM (EST) Opening Remarks
Lisa Bero, Committee Chair
11:05 IRIS Assessments Prior to the Development of the Current IRIS Handbook
Jonathan Samet, Colorado School of Public Health
Questions from Committee Members
12:00 PM Opportunity for Public Comment
12:20 End of Public Session

April 16, 2021
Web Meeting

10:00 AM (EDT) Welcome
Lisa Bero, Committee Chair
10:05 Perspectives on EPA’s IRIS Assessment Handbook
Kris Thayer (EPA)
10:50 Committee Discussion with EPA Personnel
Kris Thayer, Xabier Arzuaga, Allen Davis, Laura Dishaw, Catherine Gibbons, Barbara Glenn, Karen Hogan, Dustin Kapraun, Andrew Kraft, Elizabeth Radke, Andy Shapiro, George Woodall, and Erin Yost
11:50 Opportunity for Public Comment
12:50 PM End of Open Session
Suggested Citation:"Appendix C: Open Session Agendas." National Academies of Sciences, Engineering, and Medicine. 2022. Review of U.S. EPA's ORD Staff Handbook for Developing IRIS Assessments: 2020 Version. Washington, DC: The National Academies Press. doi: 10.17226/26289.
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Suggested Citation:"Appendix C: Open Session Agendas." National Academies of Sciences, Engineering, and Medicine. 2022. Review of U.S. EPA's ORD Staff Handbook for Developing IRIS Assessments: 2020 Version. Washington, DC: The National Academies Press. doi: 10.17226/26289.
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Page 97
Suggested Citation:"Appendix C: Open Session Agendas." National Academies of Sciences, Engineering, and Medicine. 2022. Review of U.S. EPA's ORD Staff Handbook for Developing IRIS Assessments: 2020 Version. Washington, DC: The National Academies Press. doi: 10.17226/26289.
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Page 98
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 Review of U.S. EPA's ORD Staff Handbook for Developing IRIS Assessments: 2020 Version
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The U.S. Environmental Protection Agency's (EPA) Integrated Risk Information System (IRIS) program develops human health assessments that focus on hazard identification and dose-response analyses for chemicals in the environment. The ORD Staff Handbook for Developing IRIS Assessments (the handbook) provides guidance to scientists who perform the IRIS assessments in order to foster consistency in the assessments and enhance transparency about the IRIS assessment process. At the request of the EPA, this report reviews the procedures and considerations for operationalizing the principles of systematic reviews and the methods described in the handbook for determining the scope of the IRIS assessments, evidence integration, extrapolation techniques, dose-response analyses, and characterization of uncertainties.

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