Forum on Drug Discovery, Development, and Translation: 10 Year Review: 2011-2020 (2021)

Below is the uncorrected machine-read text of this chapter, intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text of each book. Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.

Participants of The Global Crisis of Drug-Resistant Tuberculosis in BRICS Countries workshop hosted in New Delhi, India, in 2011. Special Topics The Global Crisis of Drug-Resistant Tuberculosis in BRICS Countries— A Workshop Series (2008–2013)30 The forum convened a multiyear, international initiative on multidrug-resistant tuberculosis (MDR TB), which began with a foundational workshop in Washington, DC, and included international workshops in the high-burden countries of South Africa, Russia, India, and China. To effectively treat patients diagnosed with MDR TB and protect populations from further transmission of the disease, an uninterrupted supply of quality-assured, second-line, anti-TB drugs (SLDs) is necessary. Workshop participants discussed issues related to the global drug supply chain for quality-assured SLDs for MDR TB; explored innovative solutions to delivering the right treatments to people who critically need them (e.g., strategies to improve logistics, supply and demand, quality of SLDs, and financing arrangements for the global supply chain); highlighted key challenges to controlling disease spread; and discussed innovative strategies to advance and harmonize local and international 24 efforts to prevent and treat MDR TB. 

Special Topics: Forum Activities in 2011–2020 Enabling Rapid Response and Sustained Capability with Medical Countermeasures to Mitigate the Risk of Emerging Infectious Diseases (2015)31 Global attention to recent large-scale outbreaks and their public health and medi- cal consequences has made clear that the current medical countermeasure (MCM) response system is not well adapted to rapidly respond to a large number of diverse threats through adequate development and the production of vaccines, therapeutics, diagnostic tools, and other non-pharmaceutical interventions. On March 26–27, 2015, the forum, in collaboration with the Forum on Medical and Public Health Preparedness for Catastrophic Events (now called the Forum on Medical and Public Health Preparedness for Disasters and Emergencies) and the Forum on Microbial Threats, convened a public workshop that examined how to better enable rapid and nimble private-sector engagement in the discovery, development, and translation of MCMs. This workshop explored what policies, guidance, and resources exist to guide decision making within the government and how the business and operational models employed by the private sector are affected by the policies, guidance, and available resources set forth by the U.S. government. The workshop also explored advances made by the Public Health Emergency Medical Countermeasures Enterprise to improve MCM development and translation. 39 The summaries of these workshops are available at: • Addressing the Threat of Drug Resistant Tuberculosis: Workshop Summary (IOM, 2009): https://www.nap.edu/catalog/12570. • The Emerging Threat of Drug-Resistant Tuberculosis in Southern Africa—Workshop Summary (2011): https://www.nap.edu/catalog/12993/the-emerging-threat-of-drug-resistant-tuberculosis-in- southern-africa. • The New Profile of Drug-Resistant Tuberculosis in Russia: Workshop Summary (IOM, 2011): https://www.nap.edu/catalog/13033. • Facing the Reality of Drug-Resistant Tuberculosis in India: Workshop Summary (IOM, 2012): https://www.nap.edu/catalog/13243. • Developing and Strengthening the Global Supply Chain for Second-Line Drugs for Multidrug-Resistant Tuberculosis: Workshop Summary (IOM, 2013): https://www.nap.edu/catalog/13524. • The Global Crisis of Drug-Resistant Tuberculosis and Leadership of China and the BRICS: Workshop Summary (IOM, 2014): https://www.nap.edu/catalog/18346. 31 The full text of Rapid Medical Countermeasure Response to Infectious Diseases: Enabling Sustainable Capabilities Through Ongoing Public- and Private-Sector Partnerships: Workshop Summary (NASEM, 2016) 25 is available at https://www.nap.edu/catalog/21809.