SMART Vaccines—Strategic Multi-Attribute Ranking Tool for Vaccines—is a pioneering decision-support software tool from the Institute of Medicine being developed (in collaboration with the National Academy of Engineering) to help prioritize new vaccines for development. This software tool has been developed over three phases, discussed in three reports: Ranking Vaccines: A Prioritization Framework (2012), Ranking Vaccines: A Prioritization Software Tool (2013), and Ranking Vaccines: Applications of a Prioritization Software Tool (2014).
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Emerging new infections and re-emerging diseases require new vaccines for prevention. It is difficult to decide which new vaccine to develop, especially when making investment decisions in vaccine development. Thus, decision-makers working under constrained resources need tools that can be suitable within their environment and serve as an aid in vaccine prioritization efforts.
An Introduction to SMART Vaccines
IOM President, Dr. Harvey Fineberg, introduces SMART Vaccines.
Windows (XP or above)
Click the Download SMART Vaccines button on the left and save the smart_vaccines_1-1.exe (version 1.1) file to your computer. It may take several minutes to install the software depending on your computer configuration.
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Ranking Vaccines: Applications of a Prioritization Software Tool (2014) demonstrates the practical applications of SMART Vaccines through case scenarios in collaboration with the Public Health Agency of Canada, New York State Department of Health, Serum Institute of India, and the Mexico Ministry of Health.
Ranking Vaccines: A Prioritization Software Tool (2013) discusses the methods underlying the development, validation, and evaluation of the significantly redesigned SMART Vaccines 1.0. It describes how SMART Vaccines should--and, just as importantly, should not--be used. The report provides a guiding principle and a set of strategies for future enhancements for SMART Vaccines as well as for ideas for expanded uses and considerations and possibilities for the future.
Ranking Vaccines: A Prioritization Framework (2012) describes a multi-attribute utility model to help decision makers with new vaccine prioritization. It also discusses an associated software blueprint called SMART Vaccines Beta and offers ideas for how such a software tool could be employed as a decision support system.
Included with SMART Vaccines 1.0 are Microsoft Excel files that contain data for the test vaccine candidates. The tables document the calculations and sources used to derive the necessary information. These data table provide the users guidance in ways to gather and estimate data from various sources.
There are two datasets: 1) health burden, and 2) costs associated with the disease. The Phase II report includes a detailed explanation of the methodology used to collect and estimate parameters for the software.