Immunodeficient Rodents:

A Guide to Their Immunobiology, Husbandry, and Use

Status: Available Now

Size: 260 pages, 6 x 9

Publication Year:1989

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PAPERBACK ISBN-10: 0-309-09287-6 ISBN-13: 978-0-309-09287-6	$69.00	Add to Cart

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Authors:
Committee on Immunologically Compromised Rodents, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council
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Description:
This volume is an indispensable reference on the nature of immune defects in rodents and the special techniques necessary to maintain and breed them. The authors describe 64 inbred, hybrid, and mutant strains of rodents, each with some immune defect; ...
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Table of Contents
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FRONT MATTER	i-x	(skim)
1 INTRODUCTION	1-35	(skim)
2 HEREDITARY IMMUNODEFICIENCIES	36-139	(skim)
3 INDUCED IMMUNODEFICIENCIES	140-147	(skim)
4 MAINTENANCE OF RODENTS REQUIRING ISOLATION	148-154	(skim)
5 MATING SYSTEMS FOR MUTANTS	155-160	(skim)
6 GENETIC MECHANISMS GOVERNING RESISTANCE OR SUSCEPTIBILITY . . .	161-164	(skim)
REFERENCES	165-212	(skim)
APPENDIX: HEMATOPOIETIC CELL-SURFACE ANTIGENS MENTIONED IN THE TEXT	213-216	(skim)
GLOSSARY	217-232	(skim)
INDEX	233-246	(skim)

Description

This volume is an indispensable reference on the nature of immune defects in rodents and the special techniques necessary to maintain and breed them. The authors describe 64 inbred, hybrid, and mutant strains of rodents, each with some immune defect; explain mechanisms for ensuring genetic purity; and provide a standardized nomenclature for different varieties. Subsequent sections summarize and provide references on the genetics, pathophysiology, husbandry, and reproduction of each of the various strains as well as sound advice on planning for the selection, transportation, housing, and maintenance of these animals.

Authoring Organizations

Institute for Laboratory Animal Research (ILAR)

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