Microbial and Phenotypic Definition of Rats and Mice: Proceedings of the 1998 US/Japan Conference
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Microbial and Phenotypic Definition of Rats and Mice:
Proceedings of the 1998 US/Japan Conference
(1999)
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Description

US-Japan meetings on laboratory animal science have been held virtually every year since 1980 under the US-Japan Cooperative Program on Science and Technology. Over the years these meetings have resulted in a number of important documents including the Manual of Microbiologic of Monitoring of Laboratory Animals published in 1994 and the article Establishment and Preservation of Reference Inbred Strains of Rats for General Purposes published in 1991. In addition to these publications, these meetings have been instrumental in increasing awareness of the need for microbiologic monitoring of laboratory rodents and the need for genetic definition and monitoring of mice and rats.

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Publication Info

110 pages | 6 x 9
Paperback
ISBN: 978-0-309-06591-7
Contents

Table of Contents

skim chapter
Front Matter i-x
Opening Remarks (Ota) 1-2
Opening Remarks (Vaitukaitis) 3-4
The Need for Defined Rats and Mice in Biomedical Research: Problems, Issues, and the Current State of Affairs (Nomura) 5-6
The Need for Defined Rats and Mice in Biomedical Research: Problems, Issues, and the Current State of Affairs (Tamaoki) 7-11
The Biological Integrity of Laboratory Rodents 12-14
Quality Testing System for SPF Animals in Japan and Problems in the Management of Such Systems 15-23
Definition of Microbiological Status of Rats and Mice/ The Need for Methods of Defining Flora/ International Standards for Terminology 24-27
Development of Rodent Pathogen Profiles and Adequacy of Detection Technology 28-38
Current Status of Pathogen Status in Mice and Rats 39-43
Genetic Background and Phenotypes in Animal Models of Human Diseases 44-47
Genetic and Phenotypic Definition of Laboratory Mice and Rats/ What Constitutes an Acceptable Genetic-Phenotypic Definition (Katoh) 48-57
Phenotype Assessment Requires More Than a Casual Observation 58-62
Genetic and Phenotypic Definition of Laboratory Mice and Rats/ What Constitutes an Acceptable Genetic-Phenotypic Definition (Davisson) 63-70
Genetic and Phenotypic Definition of Laboratory Mice and Rats/ What Constitutes an Acceptable Genetic-Phenotypic Definition (DeGeorge) 71-75
CIEA/NCRR/NIH Genetic and Microbiological Monitoring of Mouse and Rat Resources: Directions for the Future (Nomura) 76-77
CIEA/NCRR/NIH Genetic and Microbiological Monitoring of Mouse and Rat Resources: Directions for the Future (West) 78-82
Closing Comments/ Summary of Presentations 83-89
Summary of Presentations (Pakes) 90-91
Summary of Presentations (Nomura) 92-94
Appendix A: US/Japan Meeting Agenda 95-97
Appendix B: Meeting Participants 98-100
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Suggested Citation

National Research Council. Microbial and Phenotypic Definition of Rats and Mice: Proceedings of the 1998 US/Japan Conference. Washington, DC: The National Academies Press, 1999.

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