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Microbial Status and Genetic Evaluation of Mice and Rats:

Proceedings of the 1999 US/Japan Conference

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Status: Available Now

Size: 166 pages, 6 x 9

Publication Year:2000


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ISBN-10: 0-309-07357-X
ISBN-13: 978-0-309-07357-8
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Authors:
International Committee of the Institute for Laboratory Animal Research, National Research Council
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Table of Contents
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Front Matter i-xvi  
Opening Remarks, Judith Vaitukaitis 1-3 (skim)
Opening Remarks, Shin-Ichi Ota 4-5 (skim)
Introductory Comments on Microbiologic Testing of Laboratory Mice and Rats: Uniformity of Results 6-6 (skim)
Development of a Performance Assessment Program for Research Animal Diagnostic Laboratories and Defining Microbiologic Testing Standards 7-10 (skim)
Standardization of Rodent Health Surveillance: Regulation Versus Competition 11-15 (skim)
Factors Causing Difficulties in Uniformity of Results Among Testing Facilities in Microbiologic Monitoring of Laboratory Animals 16-20 (skim)
Necessity of Reexamining the Pathogenicity and Elimination of Parasites in Rats and Mice 21-26 (skim)
Emerging (and Reemerging) Viruses of Laboratory Mice and Rats 27-34 (skim)
Emerging Infections as a Cause of Concern 35-39 (skim)
Emerging Diseases in Mice and Rats 40-43 (skim)
Survey of Heliobacter Species in Laboratory Mice and Gerbils in Japan 44-46 (skim)
Genetic Evaluation of Outbred Rats 47-50 (skim)
Genetic Evaluation of Outbred Rats from the Breeder's Perspective 51-64 (skim)
Concept for Establishment of Rat Outbred Global Standard Strains 65-76 (skim)
Necessity of Genetic and Microbiologic Quality Network from the Pharmaceutical Industry's Perspective 77-84 (skim)
International Harmonization of Laboratory Animals 85-96 (skim)
Rat Genetics and Toxicology 97-104 (skim)
A Phenotype-driven Approach to the Molecular and Functional Analysis of the Mouse Genome 105-115 (skim)
Evaluation of Targeted Mutations 116-118 (skim)
Defining Behavioral Phenotypes in Transgenic and Knockout Mice 119-129 (skim)
Defining Phenotype in Genetically Engineered Mice 130-131 (skim)
Development of the Mouse Model Dramatype for Human Clinical Benefit 132-136 (skim)
Concluding Remarks 137-137 (skim)
Implication of Wild-derived Genes, Mitochondria, and Chromosomes in the Genetic Background of Mouse Models for Diseases and Biologic Functions 138-141 (skim)
Concluding Comments, John Strandberg 142-143 (skim)
Concluding Remarks, John Vandenbergh 144-146 (skim)
Appendix A 147-148 (skim)
Appendix B 149-150 (skim)

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