. "Appendix D: Chronology of Important Events Regarding Vaccine Safety." Immunization Safety Review: Vaccines and Autism. Washington, DC: The National Academies Press, 2004.
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Immunization Safety Review: Vaccines and Autism
Appendix D
Chronology of Important Events Regarding Vaccine Safety
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Immunization Safety Review: Vaccines and Autism
Appendix D
Chronology of Important Events Regarding Vaccine Safety
Year
Vaccine Licensure
Legislation and/or Policy Statements
IOM Reports on Vaccine Safety
1955
Inactivated poliomyelitis vaccine (IPV) available
1963
Oral poliomyelitis vaccine (OPV) available, replaces IPV
Measles vaccine available
1967
Mumps vaccine available
1969
Rubella vaccine available
1971
Measles-Mumps-Rubella
(MMR) vaccine available
1977
Mumps vaccination recommended
Evaluation of Poliomyelitis Vaccines
1979
Current formulation of rubella vaccine available, replaces earlier versions
1982
Plasma-derived hepatitis B vaccine available
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Year
Vaccine Licensure
Legislation and/or Policy Statements
IOM Reports on Vaccine Safety
1985
Hib vaccine licensed for children >15 months
1986
Congress passes P.L. 99-660, the National Childhood Vaccine Injury Act (introduced in 1984) calls for:
est. of NVPO
est. of NVAC
est. of VICP
est. of ACCV
IOM review of
(1) pertussis and rubella,
(2) routine child vaccines
1988
Evaluation of Poliomyelitis Vaccine Policy Options
1990
Two Hib conjugate vaccines licensed for use beginning at 2 months
1991
Acellular pertussis component licensed for the 4th and 5th doses of the 5-part DTP series in ACEL-IMUNE
Hepatitis B recommended by ACIP for addition to childhood immunization schedule
ACIP recommends Hib be added to childhood immunization schedule
Adverse Effects of Pertussis and Rubella Vaccines
1992
Acellular pertussis component licensed for the 4th and 5th doses of the 5-part DTP series in Tripedia
Hepatitis B vaccine: Added universal vaccination for all infants, high-risk adolescents (e.g., IV drug users, persons with multiple sex partners)
1993
Combined DTP and Hib vaccine (Tetramune) licensed
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Year
Vaccine Licensure
Legislation and/or Policy Statements
IOM Reports on Vaccine Safety
1994
Adverse Events Associated with Childhood Vaccines: Evidence Bearing on Causality
DPT and Chronic Nervous System Dysfunction: A New Analysis
1995
Varicella virus vaccine available (Varivax)
1996
DTaP vaccine licensed for first three doses given in infancy (Tripedia and ACEL-IMUNE were previously licensed for only the 4th and 5th doses).
ACIP recommends using IPV for the first 2 polio vaccinations, followed by OPV for remaining doses. Intended to be a transitional schedule for 3–5 years until an all-IPV series is available
ACIP recommends children 12 months to 12 years receive Varicella vaccine
Options for Poliomyelitis Vaccinations in the United States: Workshop Summary
1997
Additional DTaP vaccine (Infanrix) licensed for first 4 doses of 5-part series
ACIP recommends DTaP in place of DTP
Vaccine Safety Forum: Summary of Two Workshops
Risk Communication and Vaccination: Workshop Summary
1998
Additional DTaP vaccine (Certiva) licensed for first 4 doses of 5-part series
ACIP updates MMR recommendation, encouraging use of the combined MMR vaccine
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Year
Vaccine Licensure
Legislation and/or Policy Statements
IOM Reports on Vaccine Safety
1999
ACIP updates varicella vaccine recommendation, requiring immunity for child care and school entry
ACIP recommends an all-IPV schedule to begin January 2000 to prevent cases of vaccine-associated paralytic polio
AAP and PHS recommend removal of thimerosal from vaccines Also recommended postponement of hepatitis B vaccine from birth to 2-6 months for infants of hepatitis B surface antigen-negative mothers
Additional supply of thimerosal-free hepatitis B vaccine made available
MMWR notifies readers of the availability of a thimerosal-free hepatitis B vaccine, enabling the resumption of the birth dose
2000
Pneumococcal vaccine for infants and young children licensed (Prevnar)
ACIP recommends pneumococcal vaccination for all children 2-23 months, and at-risk children 24-59 months (e.g., immunocompromised)
2001
October: ACIP drafts statement expressing a preference for use of thimerosal-free DTaP, Hib, and Hep B vaccines by March 2002
Immunization Safety Review: Measles-Mumps-Rubella Vaccine and Autism
Immunization Safety Review: Thimerosal-Containing Vaccines and Neurodevelopmental Disorders
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Year
Vaccine Licensure
Legislation and/or Policy Statements
IOM Reports on Vaccine Safety
2002
Immunization Safety Review: Multiple Immunizations and Immune Dysfunction
Immunization Safety Review: Hepatitis B Vaccine and Demyelinating Neurological Disorders
Immunization Safety Review: SV40 Contamination of Polio Vaccine and Cancer
2003
Live attenuated intranasal influenza vaccine approved for use in the United States in healthy individuals aged 5-49 years old (FluMist)
ACIP recommends that children 6 to 23 months of age be vaccinated annually against influenza beginning in the 2004-2005 influenza season
Immunization Safety Review: Hepatitis B Vaccine and Demyelinating Neurological Disorders
Immunization Safety Review: SV40 Contamination of Polio Vaccine and Cancer
Immunization Safety Review: Vaccinations and Sudden Unexpected Death in Infancy
2004
Immunization Safety Review: Influenza Vaccines and Neurological Complications
