marker development are relevant to both biomedical imaging and in vitro diagnostics, in vivo imaging also entails a set of unique considerations, in part because it often requires administration of chemical agents, and thus has some similarity with drug development. Biomedical imaging will be addressed in a forthcoming workshop of the National Cancer Policy Forum, as this topic was beyond the scope of this report.
In recent decades, knowledge about the basic biology and biochemical pathways underlying cancers has increased tremendously, but translation of that knowledge to more effective patient care and better outcomes remains a challenge. Recent technological advances that enable examination of many potential biomarkers have fueled renewed interest in and optimism for developing biomarkers, and it is widely believed that biomarkers can and will be used to improve cancer screening and detection, to improve the drug development process, and to enhance the effectiveness and safety
Summary of Recommendations to Develop Biomarker-Based Tools for Cancer
Methods, Tools, and Resources Needed to Discover and Develop Biomarkers (Chapter 2)
Guidelines, Standards, Oversight, and Incentives Needed for Biomarker Development (Chapter 3)