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Environmental Medicine: Integrating a Missing Element into Medical Education (1995)
Institute of Medicine (IOM)

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. "Case Study 55: Populations at Risk From Particulate Air Pollution - United States, 1992." Environmental Medicine: Integrating a Missing Element into Medical Education. Washington, DC: The National Academies Press, 1995.

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Environmental Medicine: Integrating a Missing Element into Medical Education

above these cutoff values were derived from 1991 census figures for each county (U.S. Bureau of the Census, unpublished data, 1992).

For this report, a population at risk was defined as persons who have a “significantly higher probability of developing a condition, illness, or other abnormal status,” as described by EPA (4). Five at-risk populations were included: preadolescent children (aged ≤13 years), the elderly (aged ≥65 years), persons aged <18 years with asthma, adults (aged ≥18 years) with asthma, and persons with chronic obstructive pulmonary disease (COPD) (e.g., chronic bronchitis and emphysema). Age-specific county populations for 1991 were estimated by applying the population age distribution of each state (U.S. Bureau of the Census, unpublished data, 1992) to the counties within that state. The number of persons with asthma or COPD in each county was estimated by applying age-specific prevalences from CDC’s National Health Interview Survey (5) to age-specific population estimates for each county. Although PM10 levels are presented on a county basis, they do not indicate that all areas of the county were subject to that level or that all persons in the county were exposed to the recorded concentration.

During 1992, PM10 levels were ≥155 µg/m3 in 16 counties; an estimated 23 million persons (9.1% of the total U.S. population) resided in these counties (Table 1). Approximately 92 million additional persons (36% of the U.S. population) resided in counties in which PM10 levels were 55 µg/m3−154 µg/m3. Overall, an estimated 115 million persons (45% of the U.S. population) resided in counties with PM10 levels ≥55 µg/m3 (Table 1). In the United States during 1992, 46% of persons with asthma lived in communities with levels of particulate air pollution higher than the California standard.

TABLE 1. Estimated number and percentage of the total population and at-risk* subgroups residing in counties with particulate air pollution with a diameter of <10 µm (PM10) at levels ≥155 µg/m3 and ≥55 µg/m3—United States, 1992§

 

PM10 levels ≥155 µg/m3

PM10 levels ≥55 µg/m3

Population at risk

No.

(%)

No.

(%)

Total population

22,894,856

(9.1)

114,671,632

(45.5)

Preadolescent children (aged ≤13 yrs)

4,931,408

(9.5)

23,794,139

(46.0)

Elderly (aged ≥65 yrs)

2,649,477

(8.3)

14,010,297

(44.1)

Persons (aged <18 yrs) with asthma

387,220

(9.5)

1,878,848

(45.9)

Persons (aged ≥18 yrs) with asthma

697,444

(9.1)

3,528,475

(46.2)

Persons with chronic obstructive pulmonary disease**

1,243,407

(9.1)

6,263,409

(46.0)

*Population-at-risk estimates should not be added to form totals. These categories are not mutually exclusive.

PM10 ≥155 µg/m3 is the federal “exceedance” definition; PM10 ≥55 µg/m3 is the California “exceedance” standard.

§The PM10 level of the county does not imply responsibility for the disease status of its population.

Of the total population in the category, the proportion of each population subgroup potentially exposed.

**Includes chronic bronchitis and emphysema.

Page
905
Front Matter (R1-R12)
Executive Summary (1-4)
1 Introduction (5-13)
2 Curriculum Content (14-21)
3 Implementation Strategies (22-43)
4 Changing Medical Education (44-51)
5 Concluding Remarks (52-53)
References (54-58)
Appendixes (59-60)
A: Taking an Exposure History (61-96)
B: Medical School Courses and Clerkships: Access Points for Integrating Environmental Medicine (97-120)
C: Case Studies in Environmental Medicine (121-138)
Case Study 1: Arsenic Toxicity (139-163)
Case Study 2: Seasonal Arsenic Exposure from Burning Chromium-Copper-Arsenate-Treated Wood (164-167)
Case Study 3: Asbestos Toxicity (168-188)
Case Study 4: Benzene Toxicity (189-207)
Case Study 5: Beryllium Toxicity (208-223)
Case Study 6: Cadmium Toxicity (224-243)
Case Study 7: Fetal Death Due to Nonlethal Maternal Carbon Monoxide Poisoning (244-248)
Case Study 8: Carbon Tetrachloride Toxicity (249-266)
Case Study 9: Chlordane Toxicity (267-288)
Case Study 10: Chronic Reactive Airway Disease Following Acute Chlorine Gas Exposure in an Asymptomatic Atopic Patient (289-290)
Case Study 11: Chromium Toxicity (291-311)
Case Study 12: Cyanide Toxicity (312-331)
Case Study 13: Dioxin Toxicity (332-348)
Case Study 14: Ethylene/Propylene Glycol Toxicity (349-371)
Case Study 15: Formalin Asthma in Hospital Staff (372-373)
Case Study 16: Gasoline Toxicity (374-394)
Case Study 17: Hantavirus Pulmonary Syndrome: A Clinical Description of 17 Patients with a Newly Recognized Disease (395-401)
Case Study 18: Lead Poisoning from Mobilization of Bone Stores During Thyrotoxicosis (402-409)
Case Study 19: Lead Toxicity (410-435)
Case Study 20: Legionaires' Disease: Description of an Epidemic of Pneumonia (436-444)
Case Study 21: Mercury in House Paint as a Cause of Acrodynia: Effect of Therapy with N-Acetyl-D, L-Penixillamine (445-449)
Case Study 22: Mercury Toxicity (450-472)
Case Study 23: Methanol Toxicity (473-492)
Case Study 24: Methylene Chloride Toxicity (493-511)
Case Study 25: Paint Remover Hazard (512-515)
Case Study 26: Fatal Outcome of Methemoglobinemia in an Infant (516-517)
Case Study 27: Nitrate/Nitrite Toxicity (518-537)
Case Study 28: An Outbreak of Nitrogen Dioxide-Induced Respiratory Illness Among Ice Hockey Players (538-541)
Case Study 29: Pentachlorophenol Toxicity (542-557)
Case Study 30: Aldicarb Poisoning: A Case Report with Prolonged Cholinesterase Inhibition and Improvement After Pralidoxime Therapy (558-561)
Case Study 31: Cholinesterase-Inhibiting Pesticide Toxicity (562-584)
Case Study 32: Infertility in Male Pesticide Workers (585-587)
Case Study 33: Pesticide Food Poisoning from Contaminated Watermelons in California, 1985 (588-595)
Case Study 34: Poisoning of an Urban Family Due to Misapplication of Household Organophosphate and Carbamate Pesticides (596-604)
Case Study 35: Polynuclear Aromatic Hydrocarbon (PAH) Toxicity (605-621)
Case Study 36: Polychlorinated Biphenyl (PCB) Toxicity (622-638)
Case Study 37: Ionizing Radiation (639-673)
Case Study 38: Radon Toxicity (674-694)
Case Study 39: Residential Radon Exposure and Lung Cancer in Sweden (695-700)
Case Study 40: Community Oubreaks of Asthma Associated with Inhalation of Soybean Dust (701-706)
Case Study 41: Tetrachloroethylene Toxicity (707-726)
Case Study 42: Toluene Toxicity (727-743)
Case Study 43: Occupational Asthma Due to Toluene Diisocyanate Among Velcro-like Tape Manufacturers (744-749)
Case Study 44: 1,1,1-Trichloroethane (750-766)
Case Study 45: Trimethyltin Encephalopathy (767-771)
Case Study 46: Trichloroethylene Toxicity (772-792)
Case Study 47: Vinyl Chloride Toxicity (793-811)
Case Study 48: Work-Related Disorders of the Neck and Upper Extremity (812-813)
Case Study 49: Contact Dermatitis in Surgeons from Methylmethacrylate Bone Cement (814-816)
Case Study 50: Skin Lesions and Environmental Exposures: Rash Decisions (817-861)
Case Study 51: Acoustic Trauma Caused by the Telephone: A Report of Two Cases (862-867)
Case Study 52: Behavioral and Audiologic Manifestations of Noise-Induced Hearing Loss (868-871)
Case Study 53: Reproductive and Developmental Hazards (872-892)
Case Study 54: Childhood Asthma and Indoor Enviromental Risk Factors (893-903)
Case Study 55: Populations at Risk From Particulate Air Pollution - United States, 1992 (904-908)
D: Resources: Agencies, Organizations, Services, REferences, and Tables of Environmental Health Hazards (909-970)
E: Committee and Staff Biographies (971-975)