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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Table of Contents

Papers from a National Academy of Sciences Colloquium: Genetic Engineering of Viruses and Viral Vectors

 

 

Genetic engineering of viruses and of virus vectors: A preface
Peter Palese and Bernard Roizman

 

11287

 

 

Site-specific integration by adeno-associated virus
R.Michael Linden, Peter Ward, Catherine Giraud, Ernest Winocour, and Kenneth I.Berns

 

11288–11294

 

 

Oncogenic potential of the adenovirus E4orf6 protein
Mary Moore, Nobuo Horikoshi, and Thomas Shenk

 

11295–11301

 

 

Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma
Manuel Caruso, Khiem Pham-Nguyen, Yok-Lam Kwong, Bisong Xu, Ken-Ichiro Kosai, Milton Finegold, Savio L.C.Woo, and Shu-Hsia Chen

 

11302–11306

 

 

The function of herpes simplex virus genes: A primer for genetic engineering of novel vectors
Bernard Roizman

 

11307–11312

 

 

The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors
Samita S.Andreansky, Bin He, G.Yancey Gillespie, Liliana Soroceanu, James Markert, Joany Chou, Bernard Roizman, and Richard J.Whitley

 

11313–11318

 

 

Replication-defective herpes simplex virus vectors for gene transfer in vivo
Peggy Marconi, David Krisky, Thomas Oligino, Pietro L.Poliani, Ramesh Ramakrishnan, William F.Goins, David J.Fink, and Joseph C.Glorioso

 

11319–11320

 

 

A deletion mutant in the human cytomegalovirus gene encoding IE1491aa is replication defective due to a failure in autoregulation
Edward S.Mocarski, George W.Kemble, John M. Lyle, and Richard F.Greaves

 

11321–11326

 

 

Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains
Thomas R.Jones, Emmanuel J.H.J.Wiertz, Lei Sun, Kenneth N.Fish, Jay A.Nelson, and Hidde L.Ploegh

 

11327–11333

 

 

Epstein-Barr virus vectors for gene delivery to B lymphocytes
Erle S.Robertson, Tadamasa Ooka, and Elliott D.Kieff

 

11334–11340

 

 

Genetically engineered poxviruses for recombinant gene expression, vaccination, and safety
Bernard Moss

 

11341–11348

 

 

Applications of pox virus vectors to vaccination: An update
Enzo Paoletti

 

11349–11353



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Proceedings of the National Academy of Sciences of the United States of America PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Table of Contents Papers from a National Academy of Sciences Colloquium: Genetic Engineering of Viruses and Viral Vectors     Genetic engineering of viruses and of virus vectors: A preface Peter Palese and Bernard Roizman   11287     Site-specific integration by adeno-associated virus R.Michael Linden, Peter Ward, Catherine Giraud, Ernest Winocour, and Kenneth I.Berns   11288–11294     Oncogenic potential of the adenovirus E4orf6 protein Mary Moore, Nobuo Horikoshi, and Thomas Shenk   11295–11301     Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma Manuel Caruso, Khiem Pham-Nguyen, Yok-Lam Kwong, Bisong Xu, Ken-Ichiro Kosai, Milton Finegold, Savio L.C.Woo, and Shu-Hsia Chen   11302–11306     The function of herpes simplex virus genes: A primer for genetic engineering of novel vectors Bernard Roizman   11307–11312     The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors Samita S.Andreansky, Bin He, G.Yancey Gillespie, Liliana Soroceanu, James Markert, Joany Chou, Bernard Roizman, and Richard J.Whitley   11313–11318     Replication-defective herpes simplex virus vectors for gene transfer in vivo Peggy Marconi, David Krisky, Thomas Oligino, Pietro L.Poliani, Ramesh Ramakrishnan, William F.Goins, David J.Fink, and Joseph C.Glorioso   11319–11320     A deletion mutant in the human cytomegalovirus gene encoding IE1491aa is replication defective due to a failure in autoregulation Edward S.Mocarski, George W.Kemble, John M. Lyle, and Richard F.Greaves   11321–11326     Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains Thomas R.Jones, Emmanuel J.H.J.Wiertz, Lei Sun, Kenneth N.Fish, Jay A.Nelson, and Hidde L.Ploegh   11327–11333     Epstein-Barr virus vectors for gene delivery to B lymphocytes Erle S.Robertson, Tadamasa Ooka, and Elliott D.Kieff   11334–11340     Genetically engineered poxviruses for recombinant gene expression, vaccination, and safety Bernard Moss   11341–11348     Applications of pox virus vectors to vaccination: An update Enzo Paoletti   11349–11353

OCR for page R1
Proceedings of the National Academy of Sciences of the United States of America     Negative-strand RNA viruses: Genetic engineering and applications Peter Palese, Hongyong Zheng, Othmar G. Engelhardt, Stephan Pleschka, and Adolfo García-Sastre   11354–11358     Foreign glycoproteins expressed from recombinant vesicular stomatitis viruses are incorporated efficiently into virus particles Matthias J.Schnell, Linda Buonocore, Evelyne Kretzschmar, Erik Johnson, and John K.Rose   11359–11365     Specific infection of CD4+ target cells by recombinant rabies virus pseudotypes carrying the HIV-1 envelope spike protein Teshome Mebatsion and Karl-Klaus Conzelmann   11366–11370     Alphavirus-based expression vectors: Strategies and applications Ilya Frolov, Thomas A.Hoffman, Béla M.Prágai, Sergey A.Dryga, Henry V.Huang, Sondra Schlesinger, and Charles M.Rice   11371–11377     Early events in poliovirus infection: Virus-receptor interactions Vincent R.Racaniello   11378–11381     Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector Luigi Naldini, Ulrike Blömer, Fred H.Gage, Didier Trono, and Inder M.Verma   11382–11388     Use of virion DNA as a cloning vector for the construction of mutant and recombinant herpesviruses S.Monroe Duboise, Jie Guo, Ronald C.Desrosiers, and Jae U.Jung   11389–11394     Development of HIV vectors for anti-HIV gene therapy Eric Poeschla, Pierre Corbeau, and Flossie Wong-Staal   11395–11399     A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes Daniel S.Ory, Beverly A.Neugeboren, and Richard C.Mulligan   11400–11406     Cell-surface receptors for retroviruses and implications for gene transfer A.Dusty Miller   11407–11413     Immunization with DNA vaccines encoding glycoprotein D or glycoprotein B, alone or in combination, induces protective immunity in animal models of herpes simplex virus-2 disease William L.McClements, Marcy E.Armstrong, Robert D.Keys, and Margaret A.Liu   11414–11420     Fusigenic viral liposome for gene therapy in cardiovascular diseases Victor J.Dzau, Michael J.Mann, Ryuichi Morishita, and Yasufumi Kaneda   11421–11425