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answered. To the extent that the NIH can facilitate the development of a scientifically rigorous and relevant database, the NIH should do so.

World Health Organization

Therapeutic uses of cannabinoids warrant further basic pharmacological and experimental investigation and clinical research into their effectiveness. More research is needed on the basic neuropharmacology of THC and other cannabinoids so that better therapeutic agents can be found.


Health Council of the Netherlands

No recommendations made.

AMA House of Delegates

Controlled evidence does not support the view that THC or smoked marijuana offers clinically effective analgesia without causing significant adverse events when used alone. Preclinical evidence suggests that cannabinoids can potentiate opioid analgesia and that cannabinoids may be effective in animal models of neuropathic pain. Further research into the use of cannabinoids in neuropathic pain is warranted.

British Medical Association

The prescription of nabilone, THC, and other cannabinoids should be permitted for patients with intractable pain. Further research is needed into the potential of cannabidiol as an analgesic in chronic, terminal, and postoperative pain.

National Institutes of Health

Evaluation of cannabinoids in the management of neuropathic pain, including HIV-associated neuropathy, should be undertaken.

World Health Organization

No recommendations made, although the report notes that some newly synthesized cannabinoids are extremely potent analgesics; how-

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