Infants. For infants, the UL was judged not determinable because of insufficient data on adverse effects in this age group and concern about the infant 's ability to handle excess amounts. To prevent high levels of intake, the only source of intake for infants should be from food and formula.

Children and Adolescents. There are no reports of vitamin E toxicity in children and adolescents. Given the dearth of information, the UL values for children and adolescents are extrapolated from those established for adults. Thus, the adult UL of 1,000 mg (2,326 µmol)/day of α-tocopheryl was adjusted for children and adolescents on the basis of relative body weight as described in Chapter 4 using reference weights from Chapter 1 (Table 1-1). Values have been rounded.

Pregnancy and Lactation. There are no reports of vitamin E toxicity in pregnant or lactating women. One woman consumed 27 mg/day of α-tocopherol from the diet and 1,455 mg/day from supplements (Anderson and Pittard, 1985). Her milk α-tocopherol concentrations were more than three times normal, which might in theory be dangerous for the infant, but the mother had no adverse effects. Given the dearth of information, it is recommended that the UL for pregnant and lactating females be the same as that for the nonpregnant and nonlactating female.