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Suggested Citation:"CHEMICAL AND PHYSICAL PROPERTIES." National Research Council. 2000. Submarine Exposure Guidance Levels for Selected Hydrofluorocarbons: HFC-236fa, HFC-23,and HFC-404a. Washington, DC: The National Academies Press. doi: 10.17226/9815.
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Page 14

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HYDROFLUOROCARBON-236FA 14 2 Hydrofluorocarbon-236fa YDROFLUOROCARBON (HFC)-236FA, or 1,1,1,3,3,3-hexafluoropropane, is a gaseous halocarbon that is being considered as a replacement for the refrigerant chlorofluorocarbon (CFC)-114, which is used in centrifugal chillers aboard U.S. Navy submarines. To protect submariners from large accidental releases or low- level slow leaks of HFC-236fa, emergency exposure guidance levels (EEGLs) and continuous exposure guidance levels (CEGLs) are needed to avoid adverse health effects from short-term or prolonged exposures to HFC-236fa and to avoid degradation in crew performance. This chapter presents the available toxicity information on HFC-236fa and the subcommittee's evaluation of the Navy's proposed 1-hr and 24-hr EEGLs and 90-day CEGL. CHEMICAL AND PHYSICAL PROPERTIES

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 Submarine Exposure Guidance Levels for Selected Hydrofluorocarbons: HFC-236fa, HFC-23,and HFC-404a
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As part of the effort to phase out the use of stratospheric ozone-depleting substances, such as chlorofluorocarbons (CFCs), the U.S. Navy is considering hydrofluorocarbons (HFCs) as replacements for the CFC refrigerants used aboard its submarines. Before using the HFCs, the Navy plans to set emergency exposure guidance levels (EEGLs) and continuous exposure guidance levels (CEGLs) to protect submariners from health effects that could occur as a result of accidental releases or slow leaks.

In this report, the Subcommittee on Exposure Guidance Levels for Selected Hydrofluorocarbons of the National Research Council's (NRC 's) Committee on Toxicology independently reviews the scientific validity of the Navy's proposed 1-hr and 24-hr EEGLs and 90-day CEGLs for two of the candidate refrigerants-HFC-236fa and HFC-404a. In addition, the subcommittee reviews the the EEGLs and CEGL for HFC-23, one of the combustion products of HFC-236fa. This NRC report is intended to aid the Navy in using HFCs safely.

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