National Academies Press: OpenBook
« Previous: 7 The Data Flood: Analysis of Massive and Complex Genomic Data Sets
Suggested Citation:"8 Summary." National Research Council. 2002. Making Sense of Complexity: Summary of the Workshop on Dynamical Modeling of Complex Biomedical Systems. Washington, DC: The National Academies Press. doi: 10.17226/10356.
×

8

Summary

Throughout the workshop there was much lively discussion among the participants. It was apparent from many of the talks and mentioned explicitly during the discussions that there has been a big cultural change in mathematics and statistics in recent years. In the past, theory and models would often be developed before data were collected; that is a viable approach when dealing with fields of study that are grounded in fundamental mathematical laws (e.g., Maxwell’s equations or the Navier-Stokes equation). Now, in many areas that are attracting the attention of mathematical scientists, data drive the development of theory. This is certainly true for mathematical sciences research related to the biomedical sciences, and the resulting intellectual stimulation will likely have far-reaching effects on mathematical sciences research.

The workshop’s discussions identified three general ways in which the mathematical sciences have benefited biomedical research:

  • By suggesting insights that could not be observed directly (such as “viewing” the interior of the beating heart via a simulation);

  • By classifying and describing generic features and processes of biomedical systems; and

  • By suggesting how some biomedical systems work and what their limitations are (through tools such as dynamical analysis of mathematical models that emulate cell signaling networks).

The workshop also made clear that there is a great opportunity for many more mathematical scientists to become involved in cross-disciplinary research with biomedical scientists. A major challenge to be overcome before that interface reaches its potential is for more mathematical scientists to be exposed in depth to research in the biomedical sciences and given the opportunity to contribute. As research funding becomes increasingly available, the limiting factor becomes the availability of information about the mathematical formulations of important biomedical research. It is hoped that this workshop summary helps address that need.

Suggested Citation:"8 Summary." National Research Council. 2002. Making Sense of Complexity: Summary of the Workshop on Dynamical Modeling of Complex Biomedical Systems. Washington, DC: The National Academies Press. doi: 10.17226/10356.
×
Page 30
Next: References »
Making Sense of Complexity: Summary of the Workshop on Dynamical Modeling of Complex Biomedical Systems Get This Book
×
 Making Sense of Complexity: Summary of the Workshop on Dynamical Modeling of Complex Biomedical Systems
Buy Paperback | $21.00 Buy Ebook | $16.99
MyNAP members save 10% online.
Login or Register to save!
Download Free PDF

On April 26-28, 2001, the Board on Mathematical Sciences and Their Applications (BMSA) and the Board on Life Sciences of the National Research Council cosponsored a workshop on the dynamical modeling of complex biomedical systems. The workshop's goal was to identify some open research questions in the mathematical sciences whose solution would contribute to important unsolved problems in three general areas of the biomedical sciences: disease states, cellular processes, and neuroscience. The workshop drew a diverse group of over 80 researchers, who engaged in lively discussions.

To convey the workshop's excitement more broadly, and to help more mathematical scientists become familiar with these very fertile interface areas, the BMSA appointed one of its members, George Casella, of the University of Florida, as rapporteur. He developed this summary with the help of two colleagues from his university, Rongling Wu and Sam S. Wu, assisted by Scott Weidman, BMSA director.

This summary represents the viewpoint of its authors only and should not be taken as a consensus report of the BMSA or of the National Research Council.

READ FREE ONLINE

  1. ×

    Welcome to OpenBook!

    You're looking at OpenBook, NAP.edu's online reading room since 1999. Based on feedback from you, our users, we've made some improvements that make it easier than ever to read thousands of publications on our website.

    Do you want to take a quick tour of the OpenBook's features?

    No Thanks Take a Tour »
  2. ×

    Show this book's table of contents, where you can jump to any chapter by name.

    « Back Next »
  3. ×

    ...or use these buttons to go back to the previous chapter or skip to the next one.

    « Back Next »
  4. ×

    Jump up to the previous page or down to the next one. Also, you can type in a page number and press Enter to go directly to that page in the book.

    « Back Next »
  5. ×

    Switch between the Original Pages, where you can read the report as it appeared in print, and Text Pages for the web version, where you can highlight and search the text.

    « Back Next »
  6. ×

    To search the entire text of this book, type in your search term here and press Enter.

    « Back Next »
  7. ×

    Share a link to this book page on your preferred social network or via email.

    « Back Next »
  8. ×

    View our suggested citation for this chapter.

    « Back Next »
  9. ×

    Ready to take your reading offline? Click here to buy this book in print or download it as a free PDF, if available.

    « Back Next »
Stay Connected!