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5 Hydrogen Chloride
Pages 132-152

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From page 132... ... . Me subcommittee also identifies data gaps and recommends research relevant for dete~miriing the health risk attributable to exposure tO hydrogen chloride. Read the entire page →
From page 133... ... There are reports of severe nonIactic metabolic acidosis developing rapidly after ingestion of hydrochloric acid (suggesting systemic absorption from the gastrointestinaltract) , but this effect has not been reported after dermal exposure to concentrated hydrochloric acid or after inhalation of hydrogen chloride vapor or aeros ol. Read the entire page →
From page 134... ... Liver and kidney effects have been observed in experimental animals exposed by inhalation to hydrogen chloride, which suggests that the gas is absorbed from the respiratory tract (EPA 1994~. However, the effects also could be attributed to disturbance of acid-base metabolism or to decreased blood oxygen concentrations attendant to pulmonary damage. Read the entire page →
From page 135... ... 135 Cal 40 a; K o o so Cal o o . Read the entire page →
From page 136... ... . Pulmonary function measurements were performed, including total respiratoryresistance, thoracic gas volume at functional residual capacity, forced expiratory volume, forced vital capacity, and marginal flow at 50% and 75% of expired vital capacity. Read the entire page →
From page 137... ... At relatively low concentrations and short exposure times, hydrogen chloride can cause changes to the upper respiratory tract. Rats exposed at 200-1,500 ppm for 30 min showed a decrease in respiratory rate and minute volume, and nasal pathology (HartzeL et al. Read the entire page →
From page 138... ... 138 ., , Cal Cal Cal Cal o .~ Cut 2~ 2 ~ ED 3 ~2 2 =~' o o o o ~ ~ ~ o o o o o o o o o o o o o o .= �= �= �= �= �= �= I �� ~ �= �= �= I . Read the entire page →
From page 139... ... 139 ED ~ ~ ED rod ~ ~ ~ _ ~ Cad of ~ ~ ~ ~ ~ ~ ~ I~ ~ ~ ~` ~ (U _ _ _ _ . Read the entire page →
From page 140... ... 140 P; C ~ ~ _ ' ' 5 5 5 6, ~ E ~ a ~ 5 ~ ~ ~ cat , ' C, -I ~ c , c ~ ~ ~ ~ E ~ 5 2 ~ E ~ ~3 ~ ~ �E ~6 ~ o ('I � �~ � e . Read the entire page →
From page 143... ... 143 4= Cal An. Read the entire page →
From page 144... ... 144 .� For oo Cal '1 1 ~ o o .o V, ~ o U Q ~ (J O ~ ~0 A) Read the entire page →
From page 145... ... 145 oo V, .= Cal .~ I-o, . Read the entire page →
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From page 147... ... Nose values appear to be based on the ShonTermPublic Limits and the Public EmergencyL~m~ts (NRC 1987~. ADDITIONAL RECOMMENDATIONS FROM THE NRC AND OTHER ORGANIZATIONS Recommended exposure guidance levels for hydrogen chloride from other Organizations are surr~nzed in Table 5-4. Read the entire page →
From page 148... ... 1 h 24h NRC EEGL: 10 min 1 h 24h OSHA PEkC 1 ppm 1 ppm NRC 1987 100 ppm 20 ppm 20 ppm 5 ppm NIOSH 1990 Abbreviations: ACGI~ American Conference on Governmental Industrial Hygienists; AEGL, acute exposure guideline level; AIHA, American Industrial Hygiene Association; CEGL, continuous exposure guidance level; DFG, Deutsche Forschungsgemeinschaft; EEGL, emergencyexposure guidance level; ERPG, emergencyresponse planning guideline; IDL~ immediately dangerous to life ancl health; MAK, maximum concentration vatue in the workplace; NIOSH' National Institute for Occupational Safety and Health; NRC, National Research Council; OSHA, Occupational Safety and Heafth Admiriistration; PEL-C, permissible exposure level ceiling; ppm, pa~s per million; SMAC' spacecraft maximum adowable concentration; SPEGL, short-termpublic emergency guidance level; TLV-C, Threshold Limit Value-ceiling. Read the entire page →
From page 149... ... 1942~. Submanne Escape Action Level 2 On the basis of its review of human and expenmental animal health-effects and related data, the subcommittee concludes that the Navels proposed SEAL 2 of 25 ppm for hydrogen chionde is too conservative. Read the entire page →
From page 150... ... Limit Values anal Biological Exposure Indexes. American Conference of Governmental Industrial Hygienists, Cincinnati, OH AIHA (American Industrial Hygiene Association) Read the entire page →
From page 151... ... 1989. Ergometer within a whole-bodyplethysmograph to evaluate performance of guinea pigs under toxic atmospheres. Read the entire page →
From page 152... ... Pp. 17-30 in Emergency and Continuous Exposure Guidance Levels for Selected Airborne Contaminants, Vol. Read the entire page →

From page 132...

... . Me subcommittee also identifies data gaps and recommends research relevant for dete~miriing the health risk attributable to exposure tO hydrogen chloride.

5 Hydrogen Chloride Pages 132-152

5 Hydrogen Chloride
Pages 132-152