Making Sense of Complexity Summary of the Workshop on Dynamical Modeling of Complex Biomedical Systems (2002) / Chapter Skim
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6 Gene Transfer as a Biomedical Tool
6 Gene Transfer as a Biomedical Tool
Pages 23-25
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From page 23... ...
Eduardo Marban, of Johns Hopkins University, presented some basic background on the challenges of molecular biology, explaining, for instance, how proteins control all that we do and how DNA controls the proteins. The DNA in the human genome, if unraveled, would be about 6 feet long, and if encoded into phone books would be as high as the Washington Monument.
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From page 24... ...
. The PET reporter gene produces a signal, detectable by a PET scanner, if gene expression occurs that is, if the therapeutic gene expresses and delivers the therapy.
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From page 25... ...
25 Phelps stressed the importance of going back and forth between humans and mice, because the science is enabled by both. The advantage of the current drug therapy/delivery system is that the drug can be given in truly tiny amounts, and the promoters can be turned on externally to increase the dose.
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