Advancing Prion Science Guidance for the National Prion Research Program: Interim Report (2003) / Chapter Skim
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6. Risks to the U.S. Military
6. Risks to the U.S. Military
Pages 89-98
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From page 89... ...
forces were deployed to 144 countries outside the United States (DOD Almanac, 2002) , including several countries where bovine spongiform encephalopathy (B SK)
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From page 90... ...
Veterinary Services. Some of this beef was purchased from the United Kingdom, Italy, Germany, and Japan before it was recognized as potentially being infected with the BSE agent.
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From page 91... ...
Of this amount, 35 percent was from the United Kingdom and 65 percent was from other European countries. Of the product from the United Kingdom, approximately 300,000 pounds was delivered each month to commissary stores north of the Alps (Germany, Belgium, The Netherlands, and the United Kingdom)
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From page 92... ...
U.S. military members and their families who were living in the United Kingdom and Europe between 1980 and 1996 were at increased risk of exposure to infectious prions as a result of their consumption of locally procured beef or their consumption of beef in local eating establishments compared with the risk of their counterparts in the United States.
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From page 93... ...
RISK OF TSE INFECTION FROM BLOOD PRODUCTS Blood transfusions could also place deployed forces at risk of infection by the agent of BSE or of other transmissible spongiform encephalopathies (TSEs)
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From page 94... ...
service member has an injury serious enough to warrant a blood transfusion, there would be a theoretical risk of exposure to an infectious prion such as that which causes vCJD, but those situations are uncommon. DOD Blood Donation Deferral Policies Although the risk that a member of the deployed forces acquired a prion responsible for TSE from a blood transfusion is presumed to be very low, individuals who were deployed to Europe during the period of risk are not able to donate blood, according to DOD policy (Sparks, 2002~.
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From page 95... ...
U.S. Food arid Drug American Red Cross Administration United Kingdom (UKJ Cumulative time > 3 months 198 1996 Transfusion in UK 198~present Cumulative time ~ 3 months 198~1996 Transfusion in UK 198~present Europe aM other countries associated with BSE by USDA Europe 198~ present cumulative time > 5 years (applies to DoD after 1997)
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From page 96... ...
Until circulating PrPSc in blood can be detected with confidence, blood donation deferral policies must be based on worst-case assumptions, namely, that persons who are known to have been exposed to infectious prions and who are possibly incubating them should be deferred from the blood donor pool.
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From page 97... ...
Presentation to the IOM Committee on Transmissible Spongiform Encephalopathies: Assessment of Relevant Science, Meeting I The National Academies, Washington, D.C.
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