Review of the Biomedical Proposals to the 2005 Wright Centers of Innovation and the Biomedical Research and Technology Transfer Partnership Award Program of the State of Ohio Letter Report (2005) / Chapter Skim
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Letter Report
Letter Report
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Ann Reid. The management review explored details of the applicants' plans for the organization and administration of the proposed Atrial Fibrillation Imnovahon Center (AFIC)
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However, important tools, such as the real-hme application of cardiac electrical mapping, which would effectively localize specifically which tissue to isolate and which could help determine when atrial foci had been segregated, is not a real-hme procedure in the OR. AFIC surgical projects will try to adapt real-time electrocardiomapping to the OR environment, to improve tools available to create precise atrial lesions, and to develop techniques to perform the operation using minimally invasive techniques (as opposed to open chest surgery)
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Therefore, in addition to surgical and interventionist approaches to treating AF, a third component of the AFIC program is an examination of the variables characterizing the patient's disease, genotype and physiological status, their medical history and response to treatment. A variety of basic science projects will attempt to identify genetic, transcriptional and immunohistochemical markers associated with atnal fibrillation.
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The committee strongly recommends that a more detailed plan be developed and submitted to the state before any funds are provided and the clock started, but that the assessment process leave room for changes of emphasis as projects unfold. Should this proposal be funded the committee suggests that each component project of the entire AFIC program be required to provide acceptable milestones and deliverables on a yearly basis.
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dollar of capital funds awarded. The three-year budget plan for the center does not show expected sources of cash and in-kind contributions that meet this requirement; only $17,407,069 in cost share is shown for WCI capital funds request of $15,532,477.
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Sincerely, Barbara Hansen Chairman Committee to Review Biomedical Proposals to the 2005 Wright Centers of Innovation and the Biomedical Research and Technology Transfer Partnership Awards of the State of Ohio cc: Warren Muir Frances Sharples Ann Reid Appendix: Committee Biosketches 6
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Dr. Lenz serves on several NINDS study sections and has published numerous articles on the subjects of his research, including the biology of human cortical pain-related activity amd neurosurgical procedures for treating neuropathic pain.
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Current areas of molecular imaging and targeted drug delivery research include: 1) thrombosis and vulnerable atherosclerotic plaques, 2)
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Sun was an Adjunct Instructor of Medicine at the Hospital of the University of Pennsylvania where he provided consulting services to a large managed care organization and investigated pharmacoeconomic issues at the Leonard Davis Institute.
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and international patents in his name, his work has resulted in a large variety of medical device improvements and new technologies including the first implantable insulin pump, the rechargeable pacemaker, and highly flexible stents for placement in coronary artenes. He is also the co-inventor of a microminiaturized computer that can be implemented in the human cranial bone to sense a precursor of an epileptic seizure and prevent it from 10
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Marc G Cloutier, PhD May 3, 2005 occurring. Fischell is a member of the Space Technology Hall of Fame.
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