John R. La Montagne Memorial Symposium on Pandemic Influenza Research Meeting Proceedings (2005) / Chapter Skim
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9 Preparation for Pandemic Infuenza: Filling the Gaps in Knowledge and Understanding
9 Preparation for Pandemic Infuenza: Filling the Gaps in Knowledge and Understanding
Pages 165-178
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From page 165... ...
FINEBERG: The premise of this meeting is about research gaps and developing new knowledge needed to prepare better for pandemic flu, with a minimum time horizon of one to two years. Let me invite others, to share their thought about this meeting or what may have been missing from the meeting.
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From page 166... ...
So, I think that is something we need to work on, and help industry work toward the goals that we have for pandemic preparedness.
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From page 167... ...
To follow-up on the previous comment about the international piece, I would remind people that if we totally protected ourselves, if we had 300 million doses or 600 million, depending on the two dose regimen in the United States, we would still be devastated, because the economic consequences of a worldwide pandemic minus the United States would still have incredible implications. We saw it during SARS.
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From page 168... ...
And it would not be a bad idea for the world community to take seriously the idea that there needs to be a collaborative approach to gathering standard surveillance data sets, as well as other data sets that could be tremendously important in the event that we did get an emergence. The final comment is just that in a practical sense, for the last six months I have been trying to bring together major corporations, including the pharmaceutical industry, but also the biotechnology industry, and many other sectors of the economy to take seriously the idea of planning or thinking ahead about the potential impacts of an avian influenza pandemic.
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From page 169... ...
GE, for example, just hired a global security officer to be a bridge between the chief medical officer and the business planning people, a similar thing is going on for at Kraft Food, or any one of a number of other Fortune 500 or Fortune 1,000 companies. My suggestion is that we involve not only the chief medical officers, but also people who are increasingly tasked inside these major companies with the job of understanding what the business impacts are going to be.
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From page 170... ...
I think, if there is anything that I felt was missing at this point in time, I just do not have the sense from the meeting that there is a sense of compelling concern about moving ahead with some sort of deliberate and fairly vigorous activity to at least prepare for the next pandemic ASAP, not somewhere down the road. So, I think for me this has been a great meeting in terms of outlining a lot of needs that we have in the research field.
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From page 171... ...
Those of us who work in policy development and implementation are already working pretty hard towards how we will deliver antivirals to treat people, and how we will deliver vaccines to prevent any further harm to our societies.My plea is that the research that is taken forward is supportive of those requirements and perhaps the excitement of the science may be just bridled a little so that questions that will answer the difficult issues that we will have to face are those that come to the fore. PARTICIPANT: I think for me, pandemic planning is important, but what would be more important is to prevent a pandemic from happening.
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From page 172... ...
In the end we have to look how we can jointly create an environment which is conducive towards insuring that at the right point of time a safe and effective vaccine is going to be available.
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From page 173... ...
We are very interested in developing live attenuated virus vaccines, because we think that they are going to be especially useful in the time of pandemic for the reasons that Dr. Fauci put up on the screen during his talk.
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From page 174... ...
And it brings up an issue about in this country we have no national institute of public health in effect, that funds global collective goods. And getting the type of collaboration, whether it be for the magnitude that we are seeing ourselves dealing with, this is a magnitude of proportions that mankind sees perhaps a few times a century, but yet we all need to act together collaboratively.
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From page 175... ...
PARTICIPANT: My comment follows-up on an earlier comment, what was missing was social science research linked to all the research that was presented and discussed here -- the more basic infectious disease immunology and virology research. When a plan or strategies for the implementation phase is developed, you need to know the recipients of these strategies very well.
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From page 176... ...
Even a mild pandemic today in this "just in time" delivery model of even funeral services and burial could not handle a slight increase in the number of bodies that would need to be processed. So, I think that is again, a social science issue as much as it is actually a technology issue.
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From page 177... ...
If we are willing to take multiple perspectives, I think we are going to be able to define a convergent research strategy that is going to depend upon many actors working in a way, at a degree of coherence, and a degree of collaboration, and a degree of coordination that is unprecedented in the flu field, and maybe unprecedented in preparation in advance for any natural disaster. I am hopeful that this deliberation, this set of discussions can contribute materially to the ability of ourselves, our nation, our world to accomplish that kind of increased coherence for research.
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