Instrumentation for a Better Tomorrow Proceedings of a Symposium in Honor of Arnold Beckman (2006) / Chapter Skim
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Clinical Medicine--T. Vincent Shankey
Clinical Medicine--T. Vincent Shankey
Pages 47-50
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From page 47... ...
studied the structure and function of IgM antibodies for his dissertation. Before joining the Advanced Technology Center at Beckman Coulter, Inc., in 2001, he was the director of research for the Urology Department and scientific director of the Clinical Flow Cytometry Laboratory at Loyola University Medical Center near Chicago, Illinois, for more than 13 years.
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From page 48... ...
While fluorescence may occur naturally, cells are usually stained with fluores cent dyes that bind specifically to cellular constituents. The intensity of the resulting fluo rescence emission is measured at several wavelengths simultaneously to identify the quantities of specific components of the cells.
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From page 49... ...
Flow cytometers also are used in many other applications. For example, when a patient comes to a doctor's office with what appears to be leukemia or lymphoma, the disease is characterized using multiple sets of cell surface markers.
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From page 50... ...
We need to monitor biomarkers to know when to start giv ing people therapies, and then monitor when to increase or decrease those therapies. To achieve this goal, instruments need to be straightfor ward and robust, with relatively automatic data FIGURE 25 A color photograph of a flow cytometer showing the analysis and interpretation.
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