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8 Analysis Structure
Pages 33-38

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From page 33...
... The variables included in the basic analyses are participant status, SHAD participant exposure group, age, race, branch of service, pay grade, smoking, drinking, body mass index (BMI; weight in kilograms divided by height squared, in meters) , vital status, date of death, cause of death, and SF-36 score.
From page 34...
... Yes Questionnaire Perception of likelihood of long-term physical or mental effects* Somewhat unlikely Questionnaire Number of SHAD trials 3 Military records Specific information about test and post-test activities Yes Questionnaire/military records Name of ship USS George Eastman DoD fact sheet Type of agent used in test Trioctyl phosphate DoD fact sheet Number of days or dates on ships 35 or 7/1–8/5/1972 Military unit records Vital status Alive National Death Index/SSA/VA records Date of death 8/15/2000 National Death Index/SSA/VA records Cause of death ICD-9 code National Death Index Branch of service Navy Military records Pay grade E1 Military records *
From page 35...
... Removing the participants in groups A and B from further consideration, the remaining participants fell into two remaining groups: group C included participants who were at any test using active agents; and group D included participants who were at tests where no active agents were used. Thus, group D subjects might have been exposed to any one of the following agents or decontaminants: BG, betapropriolactone, calcofluor, DF-504, diethylphthlate with fluorescent dye, Echerichia coli, fluorescent particles, MAA, Serratia marcescens, trioctyl phosphate, uranine dye, or zinc cadmium sulfide.
From page 36...
... * BG = Bacillus globigii; MAA = methylacetoacetate; TOF = trioctyl phosphate; nerve agents = sarin or VX; biological agents = Coxiella burnetti, Pasteurella tularensis, staphyloccocal enterotoxin B; no active agents = remainder of participants after Groups A, B, and C have been removed that were exposed to some other type of agent.
From page 37...
... Morbidity Analyses The main morbidity analysis focused on differences between Project SHAD participants and nonparticipant controls for the primary outcome of the SF-36 score, physical and mental summary scores. Differences in secondary and tertiary outcomes as described above were also examined.
From page 38...
... Crude comparisons of prevalence of these outcomes, as well as comparisons of the prevalence of medical conditions and symptoms, were conducted using odds ratios and 95 percent CI. Comparison of prevalence rates adjusted for the potential confounders of age, race, pay grade, smoking, drinking, and BMI was done using logistic regression analysis.


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