Foodborne Disease and Public Health Summary of an Iranian-American Workshop (2008) / Chapter Skim
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3 Selected Gastrointestinal Diseases in Iran and Their Investigation
3 Selected Gastrointestinal Diseases in Iran and Their Investigation
Pages 27-36
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From page 27... ...
The Research Center for Gastroenterology and Liver Diseases also has a keen interest in causes of gastrointestinal disease that may not be foodborne; in this vein, Hosein Dabiri Jaldebakhani described the research center's investigations of Helicobacter pylori, and Mohammad Reza Zali described the burden of gastrointestinal disease in Iran. Key points from the discussion appear at the end of the chapter.
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From page 28... ...
Ardalan listed several Iranian laboratories involved in the analysis of foodborne diseases, along with the activities that take place in each: • Food and drug laboratories under the supervision of the Ministry of Health and Medical Education: diagnostic microbiology, virology, and other areas using traditional methods • Institute Pasteur of Iran: the diagnosis of Enterobacteriaceae by traditional and molecular methods, the diagnosis and typing of Vibrio cholerae, and the use of molecular typing methods
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From page 29... ...
None of the isolates belonged to the O157:H7 serotype. THE RESEARCH DEPARTMENT OF FOODBORNE AND DIARRHEAL DISEASES Presenter: Fereshteh Jafari The Research Department of Foodborne and Diarrheal Diseases was established in 2000 under the auspices of the Research Center for Gastro
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From page 30... ...
The functions of the Research Department of Foodborne and Diarrheal Diseases include the following: • The isolation and identification of foodborne pathogens • The serotyping and determination of antimicrobial susceptibility • Finding patterns of foodborne pathogens using molecular techniques • The preservation of isolated strains • The maintenance of its culture collection Jafari showed slides listing many of the techniques used in the molecular laboratory, from the basic staining techniques to the more advanced molecular biology techniques. He also highlighted the interests and methods of the four reference laboratories for foodborne diseases: bacteriology, virology, pathology, and polymerase chain reaction (PCR)
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From page 31... ...
The predominant genotypes in Iran are G4 and G1. A study in the Research Department of Foodborne and Diarrheal Diseases looked extensively at the epidemiology of rotavirus infection and found very high rates of infection among infants and children younger than 2 years of age, with a peak incidence among children 7 to 12 months old.
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From page 32... ...
From July 2005 to January 2007, the investigators collected 3,826 fecal samples from three different areas of Iran. Mojarad briefly described the methods and showed slides covering the sample collection by sex and by geographic area, the frequency of E
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From page 33... ...
Related ongoing projects conducted by the Research Center for Gastroenterology and Liver Diseases include the phylogenic analysis of various Salmonella serotypes in Iranian isolates and the investigation of extendedspectrum beta-lacamase-producing bacteria in various isolates. HELICOBACTER PYLORI IN IRAN Presenter: Hosein Dabiri Jaldebakhani Infection with Helicobacter pylori is highly prevalent in Iran.
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From page 34... ...
pylori strains that have been isolated from Iranian patients with and without gastric ulcers THE BURDEN OF GASTROINTESTINAL DISEASE IN IRAN Presenter: Mohammad Reza Zali Overview The purpose of assessing the burden of gastrointestinal disease in Iran is to help guide strategies for its prevention and treatment. Gastrointestinal disorders pose a huge burden on society.
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From page 35... ...
Among the diseases that are increasing in incidence are esophageal and colorectal cancer, hepatitis C, nonalcoholic fatty liver disease, cirrhosis of the liver, Barretts esophagus, pancreatitis, gallstones, diverticular disease, celiac disease, and irritable bowel syndrome. Study Description To obtain current and accurate information on the burden of disease in Iran, Mohammad Reza Zali and colleagues designed a study under the sponsorship of the Shaheed Beheshti University in Tehran.
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From page 36... ...
Participants also raised questions about different forms of hepatitis and their possible relationship to liver disease in Iran, about possible connections between foodborne pathogens and the long-term diarrhea associated with inflammatory bowel disease, about studies comparing traditional medicine with antibiotic therapy in the control of diarrhea (none has been done) , about the prevalence of norovirus infections in Iran (data unavailable)
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