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Appendix C: Epidemiology of Colorectal Cancer and Colorectal Cancer Screening: A Background Paper
Pages 101-110

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From page 101...
... . The estimated lifetime probability at birth of developing colorectal cancer in the United States is approximately 6 percent, and the probability of dying from the disease is about 3 percent (NCI, 2004)
From page 102...
... In the United States, between 1973 and 1995, mortality declined by 20 percent and incidence declined by 7 percent. Both continued to decline from 1995 to 2003 (NCI, 2006)
From page 103...
... The data on Hispanic and non-Hispanic mortality for these states may be unreliable for the time period used in the generation of the trend (1990–2001) and has been excluded from the calculation of the United States recent trend.
From page 104...
... . Risk factors Individuals with hereditary conditions such as familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer have a significantly increased risk of colorectal cancer, but combined, these two conditions do not account for more than 5 to 6 percent of all cases of colorectal cancer.
From page 105...
... In the United States, there are 153,760 cases per year and 52,180 deaths. Source: Parkin et al.
From page 106...
... . Screening Use Despite the proven effectiveness of screening and the availability of several different tests, overall rates of screening remain low in the United States and other developed countries.
From page 107...
... . Few studies have examined practice-level factors, but limited evidence suggests that use of reminder systems, and possibly use of mul tidisciplinary teams, are associated with more frequent colorectal cancer screening (Hudson et al., 2007)
From page 108...
... 50 40 Percentage 30 20 10 0 1987 1989 1991 1993 1995 1997 1999 2001 2003 Year Any recommended test CRE in past 3 years Colonoscopy in past 10 years Sigmoidoscopy in past 5 years Figure C5 stacked version, R01298.
From page 109...
... NOTE: CRE = colorectal endoscopy. Source: Figure and note reprinted, with permission, from "Patterns of colorectal cancer screening uptake among men and women in the United States," 2006.
From page 110...
... 2006. Patterns of colorectal can cer screening uptake among men and women in the United States.


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