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HIV and Disability Updating the Social Security Listings (2010) / Chapter Skim
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Appendix C: HIV Background Tables
Pages 157-162

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From page 157...
... Table C-2 provides a nonexhaustive list of HIV/AIDS antiretroviral drugs and their potential side effects.
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From page 158...
... • Hepatic cirrhosis • Candidiasis of bronchi, trachea, lungs, • HIV-associated nephropathy oresophagus • Mental disorders • Coccidioidomycosis, disseminated or - Anxiety extrapulmonary - Bipolar disorder • Cryptococcosis, extrapulmonary - Depression • Cryptosporidiosis, chronic intestinal > 1 • Neutropenia month • Non-AIDS malignancies • Cytomegalovirus disease (other than liver, - Cancer of the anus spleen, or nodes) - Cancer of the larynx • Encephalopathy, HIV-related - Cancer of the mouth or pharynx • Herpes simplex (chronic ulcers > 1 month, - Cancer of the penis bronchitis, pneumonia, or esophagitis)
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From page 159...
... Abacavir and Epzicom August 2, • Hypersensitivity reaction lamivudine 2004 Abacavir, Trizivir November • Cardiovascular effects zidovudine, and 14, 2000 • Hyperlipidemia lamivudine • Hypersensitivity reaction • Lactic acidosis/hepatic steatosis +/– pancreatitis (severe mitochondrial toxicities) • Lipodystrophy • Stevens-Johnson syndrome • Toxic epidermal necrosis Abacavir sulfate, Ziagen December • Hypersensitivity reaction ABC 17, 1998 • Lipoatrophy • Myocardial infarctions Didanosine, Videx October • Lactic acidosis dideoxyinosine, ddI 9, 1991 • Pancreatitis • Peripheral neuropathy Emtricitabine, FTC Emtriva July 2, • Lactic acidosis 2003 • Lipoatrophy Enteric-coated Videx EC October • Cardiovascular disease didanosine, ddI EC 31, 2000 • Gastrointestinal intolerance • Hepatotoxicity • Hepatic steatosis +/– pancreatitis (severe mitochondrial toxicities)
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From page 160...
... • Lipodystrophy • Nephrotoxicity • Osteopenia • Pancreatitis • Peripheral neuropathy Tenofovir Viread October • Lipoatrophy disoproxil fumarate, 26, 2001 • Nephrotoxicity TDF • Osteopenia • Pancreatitis Zalcitabine, Hivid June 19, • Unknown dideoxycytidine, 1992 ddC (no longer marketed) Zidovudine, Retrovir March 19, • Bone marrow suppression azidothymidine, 1987 • Gastrointestinal intolerance AZT, ZDV • Hepatotoxicity • Hyperlipidemia • Insulin resistance/diabetes mellitus • Lactic acidosis/hepatic steatosis +/– pancreatitis (severe mitochondrial toxicities)
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From page 161...
... 17, 1998 • Neuropsychiatric side effects • Short-term central nervous system toxicity Etravirine Intelence January • High blood pressure 18, 2008 Nevirapine, NVP Viramune June 27, • Hypersensitivity with hepatic failure 1996 Protease Inhibitors (PIs) Amprenavir, APV Agenerase April 15, • Stevens-Johnson syndrome 1999 • Toxic epidermal necrosis Atazanavir sulfate, Reyataz June 20, • Jaundice ATV 2003 • Kidney stones Darunavir Prezista June 23, • Hepatotoxicity 2006 Fosamprenavir Lexiva October • Cholesteremia calcium, FOS-APV 20, 2003 Indinavir, IDV Crixivan March 13, • Kidney stones 1996 • Nephrotoxicity Lopinavir and Kaletra September • Cardiovascular risk ritonavir, LPV/RTV 15, 2000 Nelfinavir mesylate, Viracept March 14, • Diarrhea NFV 1997 Ritonavir, RTV Norvir March 1, • Pancreatitis 1996 Saquinavir (no Fortovase November • N/A longer marketed)
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From page 162...
... Morbidity and Mortality Weekly Report 43:1–10.
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Key Terms

  • peripheral neuropathy
  • toxic epidermal
  • epidermal necrosis
  • mitochondrial toxicities
  • hypersensitivity reaction

  • hepatic steatosis
  • lactic acidosis
  • neuropathy tenofovir
  • cardiovascular risk
  • gastrointestinal intolerance

  • kidney stones
  • disoproxil fumarate
  • abacavir sulfate
  • drug interactions
  • trizivir november

  • cholesteremia calcium
  • disease didanosine
  • emtriva july
  • intolerance azt
  • epzicom august

  • wasting syndrome
  • jaundice atv
  • nephrotoxicity lopinavir
  • myocardial infarctions
  • effects zidovudine

  • interactions mesylate
  • necrosis abacavir
  • progressive multifocal
  • central nervous
  • blood pressure


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