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Session V: Medical Opportunities in Hawaii
Pages 110-124

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From page 110...
... The care of human life and happiness, and not their destruction, is the first and only objective of good government. Without health, there is no happiness." She emphasized the collaborative work of the health sciences, in which Hawaii sought to integrate its particular strengths of basic sciences, nursing, medicine, social work, cancer research, and public health.
From page 111...
... A second was the hospitals' growing experience with clinical trials. He noted that Hawaii's uniquely diverse population made it an ideal location for clinical trials, and that true local expertise in the medical care of Asian Pacific populations was likely to draw patients not only from Hawaii but also from throughout the Pacific Rim region.
From page 112...
... The company, internationally known for photomultiplier tubes used in satellites imaging and astronomy observatories, wanted to site a PET scanner prototype in the United States. They proposed a joint venture with Queen's to build a $5 million cyclotron facility to manufacture the radiopharmaceuticals for PET imaging while Hamamatsu Photonics provided the pro totype PET scanner.
From page 113...
... It trains not only doctors, he said, but also public health officers, medical technologists, speech pathologists, and basic scientists. "We have probably the most diverse student body population and faculty of any medical school in not only the United States, but in the world." Of the current medical school class, 64 were chosen from 1,800 applications; 90 percent of the students are residents of Hawaii.
From page 114...
... In a related program, the school participates in the National Children's Study in which 1,000 Oahu children are to be carefully monitored from the pregnancy of the mother through their lifetime. At the other end of the age spectrum, he said, the school's Department of Geriatric Medicine is nationally recognized, partly for its nationally ranked educational and research programs tailored to Hawaii's diverse communities.
From page 115...
... Another way is through new business models that are health focused, use alternative delivery systems, and minimize redundancy in care delivery. "We need to know why some treatments work for some individuals and not for others," he said.
From page 116...
... Lee, deputy director of the National Cancer Institute (NCI) Center for Strategic Scientific Initiatives, noted that cancer is known to be not one but many diseases, and that many are "relatively manageable" when the disease is detected early and localized.
From page 117...
... " Cancer has always been thought of as a disease of the genes, but everyone had their own way to characterize these changes in small sample sets. He said we took the community's first recommendation of standardization and decided to do a systemic identification of all genomic changes at a large-scale by multiple teams, repeat it for all cancers, make the data publicly available in real time, and test whether the data could be assembled in a format akin to a chemical engineering steam table.25 Efforts to accomplish this started in 2004, and in 2007 the Center launched The Cancer Genome Atlas (TCGA)
From page 118...
... Unfortunately, as assessed by the National Academies, technologies used to detect protein changes were not yet mature enough as compared to those used by TCGA to examine genomic alterations. As such, the Center launched a pro gram in 2006 to get proteomic technologies ready for clinical utility.
From page 119...
... Also, it helps that we gave them the mechanism to exchange personnel, and it's probably not going to be a very hard sell to have one of these professors send a post-doc or graduate student to Hawaii to collaborate with your existing infrastructure." He thanked the organizers for the opportunity to describe "what we see as the potential for the future of personalized health medicine." BIOMEDICAL INNOVATION WITH GLOBAL IMPACT IN HAWAII Hank Wuh Skai Ventures Cellular Bioengineering, Inc.
From page 120...
... He had moved back to Hawaii seven years ago to take care of his father and to run his company Skai Ventures. Why Start-ups are "Really Hard" He began by acknowledging that start-up companies "are really hard" and gave a brief personal reminiscence about the experience.
From page 121...
... In the process of developing artificial corneas, Skai built expertise in materials science -- specifically in a binding property between the polymer and the surrounding environment. When the Air Force put out a re quest for proposals for a polymer gel that could bind radioactive particles, Skai responded.
From page 122...
... He noted a Hawaiian proverb that says, "This banana tree is exceedingly strong only because everybody got together to produce this single fruit." He noted an inability of the medical community "to really move into Hawaiian communities without scaring them away." How might we produce an environment, he asked, that brings in the Hawaiian people, who have so many health needs? A Department of Native Hawaiian Health Dr.
From page 123...
... NIH is running out of storage space, he said, and The Cancer Genome Atlas is having to send discs of data to other centers for processing. "I think there's some real power to be investing both in the manpower and in the informatics and IT infrastructure." Dr.
From page 124...
... He added that he had been asked to estimate the minimum data capacities for the state, and had answered that 100 megabits of capacity should be provided for every home in Hawaii, and 1-10 gigabits for scientific research and business research. "These are absolutely mandatory thresholds," he said, "if you want to have a high-tech industry that's stable and grows." In addition, he said, the computer science ca pacity and supportive technologies at UH are not sufficient.


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