Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories Summary of a Workshop (2012) / Chapter Skim
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2 Framing the Issue (Plenary Sessions)
2 Framing the Issue (Plenary Sessions)
Pages 17-26
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From page 17... ...
She observed that it was an important and timely meeting and an opportunity to synthesize lessons learned from prior experience and to suggest strategies for moving forward. She then introduced the three main priorities of the United States State Department's Biosecurity Engagement Program (BEP)
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From page 18... ...
PLENARY PRESENTATIONS United States Biosafety Experiences During the Last Two Decades: Lessons and Achievements The first speaker in this session was Peter Palese (Mount Sinai School of Medicine, United States) , who described the United States requirements for biosafety and biosecurity from the point of view of a working scientist.
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From page 19... ...
About five years ago, the 1918 influenza virus, which he helped reconstruct (Tumpey et al., 2005) , was added to the United States Select Agents list, which controls the possession, use, and transfer of the hazardous pathogens classified as Select Agents in the United States.
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From page 20... ...
Containment Labs: Who Wants Them, Who Funds Them, and Why Jennifer Gaudioso (Sandia National Laboratories, United States) described the recent expansion in the number of high biological containment labs worldwide as well as some of the factors motivating lab construction.
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From page 21... ...
Although the LANL lab was built seven years ago, it is still not functional. Without a BSL-3, SNL found strategic partners, invested in molecular techniques including sequencing, and was able to play a role in the Amerithrax investigation.10 DISCUSSIONS During the discussion, several participants shared stories of how containment labs had helped their country characterize and control disease outbreaks.
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From page 22... ...
The second talk described challenges commonly encountered in Southeast Asia and questioned whether the current trend of developing countries adopting energy and technology intensive laboratory design standards from the West will continue. PLENARY PRESENTATIONS Laboratory Capacity, Biosafety, and Biosecurity in Africa: Gaps, Goals, Needs, and Progress Willy Tonui (African Biological Safety Association [AfBSA]
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From page 23... ...
AfBSA currently sees opportunities to promote international partnerships, to work with governments to develop biosafety and biosecurity standards, to enhance collaboration and networking among laboratories, to help African laboratories implement risk assessment principles, and to design and implement biosafety training programs. Several African countries have formed or are forming their own national biosafety organizations to pursue similar goals within their borders.
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From page 24... ...
are commonly used world-wide both to allow labs to apply for United States research funding and because biosafety professionals helping with a foreign project often import their own practices. WHO's Laboratory Biosafety Manual (LBM)
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From page 25... ...
A few hypothesized that the increasing availability of molecular diagnostic methods, which have the potential to replace culture-based tests, will reduce the demand for new BSL-3 and BSL-4 labs, while others felt that the pace would continue or increase with every country or institute wanting their own lab. One conjectured that the factors driving capacity have changed; where previously labs were desired simply to diagnose dangerous pathogens, increasing travel and difficulty in containing diseases within national borders has increased the demand for cures, which requires research.
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