Transforming Glycoscience A Roadmap for the Future (2012) / Chapter Skim
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Appendix A: Committee Member Biographies
Appendix A: Committee Member Biographies
Pages 159-166
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From page 159... ...
He has received numerous national and international awards and honors for his fundamental and applied work in the field of optical sensors and arrays, including the American Chemical Society's 2010 National Award for Creative Invention. He is a member of the National Academy of Engineering, a fellow of the American Institute for Medical and Biological 159
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From page 160... ...
spectroscopy and fundamental studies in the fragmentation of carbohydrate molecules by mass spectrometry, with the overall goal being to assign the detailed structures of these complex molecules unambiguously. His laboratory is also interested in a series of glycosyltransferases involved in synthesis and branching of novel core structures of glycoprotein oligosaccharides and in better understanding the control of expression and the role of these enzymes in different tissues.
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From page 161... ...
She is a member of the National Academy of Sciences, the Institute of Medicine, the American Academy of Arts and Sciences, and the German Academy of Sciences Leopoldina. Some awards of note include the LemelsonMassachusetts Institute of Technology award for inventors, the Whistler Award, the Ernst Schering Prize, a MacArthur Foundation Fellowship, the American Chemical Society Award in Pure Chemistry, the Tetrahedron Young Investigator Award, and the Irving Sigal Young Investigator Award of the Protein Society.
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From page 162... ...
Research by the Boons Group deals with the synthesis and biological functions of carbohydrates and glycoconjugates. The diverse topics to which the group has made significant contributions include the development of new and better methods for synthesizing exceptionally complex molecules, the use of new methods in the synthesis and study of properties of complex carbohydrates of increasing size and complexity, the development of synthetic cancer and bacterial vaccines, the design and synthesis of glycosidase inhibitors, and the use of synthetic compounds for the study of innate immunity.
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From page 163... ...
Her interdisciplinary research interests focus on elucidating and exploiting the biological roles of oligosaccharides and oligosaccharide conjugates in biological systems. Some examples of her contributions include a new approach to inhibiting cell wall biosynthesis in Mycobacterium tuberculosis to devising sugar-binding surfaces to grow human embryonic stem cells.
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From page 164... ...
His own research efforts prior to joining Genentech focused primarily on discovering functions for cell surface glycans in mammalian organisms, with particular relevance to the immune system. His role as senior director of pathology at Genentech includes opportunities to continue this research in an outstanding, disease-focused scientific environment while also leading the growth and development of scientific discovery and research support activities of the pathology department at Genentech.
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From page 165... ...
Sasisekharan's group was the first to conduct detailed studies of a class of glycan-degrading enzymes that were revealed to be critical tools to uncover fundamental biological roles of glycans in diseases including cancer, cardiovascular biology, and infectious diseases.
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From page 166... ...
Dr. Varki has received a MERIT Award from the National Institutes of Health, an American Cancer Society Faculty Research Award, the Karl Meyer Award of the Society for Glycobiology, and the International Glycoconjugate Organization Award.
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