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Infectious Diseases of Mice and Rats (1991) / Chapter Skim
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11. Genitourinary System
Pages 231-235

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From page 231...
... Mycoplasma muris, an anaerobic mycoplasma, has been isolated from the vaginas of mice in a single colony. Natural infections of M
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From page 232...
... The methods of cultivation, identification, and serologic testing for leptospiral organisms are highly specialized and usually are performed by specialty laboratories (Sulzer and Jones, undated; Turner 1968, 1970~. Specimens from human patients are usually submitted through county and state departments of public health to the Centers for Disease Control.
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From page 233...
... During the leptospiruric phase the organism can be demonstrated in renal tubules by using histologic sections stained by silver impregnation methods such as Warthin-Starry (Friedmann et al., 1973~. Diagnosis The most common diagnostic method is serology in which the microscopic agglutination test with live antigen is used.
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From page 234...
... It is a strict anaerobe that grows only on SP-4 medium (not on standard horse serum and yeast extract medium suitable for other rodent mycoplasmas) , and hydrolyzes arginine.
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From page 235...
... The agent presumably can be eliminated by cesarean derivation and barrier maintenance. Interference with Research Unknown.
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Key Terms

  • interrogans serovar
  • leptospira interrogans
  • laboratory mice
  • reservoir hosts
  • leptospiral organisms

  • mycoplasma muris
  • anaerobic mycoplasma
  • primary reservoir
  • wild rodents
  • diet containing

  • contemporary stocks
  • diagnostic laboratories
  • animal disease
  • recently isolated
  • usually submitted

  • order spirochaetales
  • wild rats
  • order mycoplasmatales
  • chlortetracycline hydrochloride
  • silver impregnation

  • strict anaerobe
  • occurs naturally
  • similar genital
  • infected mice
  • single colony

  • standard horse
  • diagnosis requires
  • histologic sections
  • specialty laboratories
  • highly specialized


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