Medically Assisted Conception An Agenda for Research (1989) / Chapter Skim
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Ovarian Stimulation in Non-Human Primates
Ovarian Stimulation in Non-Human Primates
Pages 117-129
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From page 117... ...
of the trial cycle are a gecxretric increase ~ peripilera1 An con~nt~tions of estradiol, Arching fern the maturing follicle, midcycle surges of Ill and F5H, irx~uced by the rising estradiol levels, and two ~ ; of pr ~ terone secretion face, the corpus luteum, a differentiated structure derived foul the ovulatory follicle. With diminished function of the corpus lubes, progesterone levels decline and menstruation occurs.
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From page 118... ...
, the intuition of OH levels by es~actiol se~cic~n f m n this follicle, thus dinting available FSH for follicles requiring greater support than the dominant follicle. Irrespective of the r~ch~urism, it is evident that the dominant follicle precludes the development of other follicles daring the second week of the follic~1ar phase.
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From page 119... ...
, human follicle stimulating hormone (l4) , pregnant mare's serum gYxeKkstrqpin (15)
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From page 120... ...
of lute1 tissue following hCG treatment, pmg~tercrm Ratio are markedly greasy ~ the luteal phase of slime cycles relative t:o Be It's pycle (13~. Hover, despite ideas Procter Sties, the faction of the luteal tissue is diminish relative to normal t;=C~e.
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From page 121... ...
~lems with Stimulated Ovarian Fashion As described above, the response to exoqenals ganadotr~in therapy maybe he~en~us, with varying degrees of folliallar develc~ and variable ~ maturation. Earl of this heterugenei~r Is due to Be endocrine milieu of the subject ardor the errs of a premature In surge.
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From page 122... ...
By what n~x~nism dog "selection" of the dominant follicle occur and how is dcminanm" of the periovulatory follicle sustained? When ovarian function is stimulated by exogenous gonadotro pies, what pool of follicles is responsive to this ~crea~nent?
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From page 123... ...
, a member of the inhibin family which indurate= FSH secretion, may be ~ eful for ovarian stimulation. In the future, when its actions are understood and it is available, it or an agonistic analog may be fur An prorating ovarian stimulation.
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From page 124... ...
A~I~ We a==istar~e of Martha Forester, Dara I~azy, and Patricia R - se In the preparation of grciEhics are We manuscript is sincerely ~r~ia~.
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From page 125... ...
~ c' ad ~ o o ~ oh en o ~ o on em o Ad c)
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From page 126... ...
a' at · ~ cn o cO ~ z ~ O ~ IL lo O O O O O v O O 00 ~ ct so Cal ~ O O ~ 1~/5n HI o 0 o ~ ~ .
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From page 127... ...
German AL, Em: Nixon, DK Johnson, and GD H - en (1977) P - ulaticnl of follialloger=;is in the cycling rhesus By: Selection of the dominant follicle.
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From page 128... ...
JS Ott~bre (1986) Characterization of corpora lutea in Parleys after s~vulation with human menopa~~~1 gonadotropin or follicle stimulating hormone.
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From page 129... ...
Refractoriness of Remus monkeys to r ~ ated Ovarian sting ration by edgers s gaoadotrc pins is caused by nonprecipitating antibodies. Am J Reprod Immun Micro biol Us:.
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