Medically Assisted Conception An Agenda for Research (1989) / Chapter Skim
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Uterine Receptivity, Maternal Recognition of Pregnancy and Early Embryonic Loss
Uterine Receptivity, Maternal Recognition of Pregnancy and Early Embryonic Loss
Pages 319-335
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From page 319... ...
Magnitude of Embryonic Tom= considerable prenatal Mortality probably Ark; in all Ills. In the Inman, a Belies that exhibits Fly high Ate= of embryonic 1~=, a Foul pregnant ooours ally ~ abut 1 in 5 trial—:les in Karen having regular interfere arm not practicing mxlt~ception (l)
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From page 320... ...
First, lethal genes may be expressed in embryo early development upon activation of the embryonic genome in pigs. Evidence for embryonic I~== ~ ~ to the presence of lethal genes incus sire differences as they relate to -echoic mortality rate (9)
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From page 321... ...
e IN this polyp - BYTE= species, eicNgate~ conceptuses arrange themselves end to end, each occupying not more than 10 to 20 cm of uterus ~ they follow the con tours of the v.;1lous folds of the endbretrium. Mbreover, the uterine epithelium is never eroded throughout pregnancy.
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From page 322... ...
It Is for this reason that uterine secretions (or hi~Wcr~e) are ~3ht to play a marital role in of the pig are In War bevies Were an irrvasive type of i~lantati~ either ~ ret over or Taxer'; relatively late in pry (17)
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From page 323... ...
Thus these aresults are indicative of the likely importance of uterine secreticos in selecting against asynchronous embryo;. UhfortLna+^ly, in the majority of experiments testing asynchrony in the sheep, the precise tote and stage of embryonic development at which death occurs has not keen accurately established.
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From page 324... ...
of the human is a pit of the uterine ppithelium during the secretory phase of the chicle arm airing the first tri~ter of pro. EP 15 has significant may s;~;lari~ to proteins of the 9-lac~l~n gene fairy whit include its that bind tiny arx1 a variety of the Molar ligates (34)
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From page 325... ...
These categories include nutrient and hormone transport molecules, growth factors, pro tease inhibitors, antimicrobial components and ~ restive agents. Others may be involved in pro meting implantation or attachment.
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From page 326... ...
Ire 1~= of bus embryos might well result f`~ an ina~r~riate Halite, quantity or even tactic nature of uterine sureties. Even Hen brat Troy exists between an Kayo arm the Other, a hormonal profile similar to that conserved c3urir~ a normal pregnancy mast be Attain if _: are to survive In a Other be Caries have been roved.
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From page 327... ...
Unfor~at~ly, that limited X~wl~ge that alrrmdcly exists has largely bun derived fm~ Do, a series ~i may not be an a~roprmte PI for Canals Cat coo scat have an invasive type of pla~aticx~. He rejec tian of embryos by the maternal imp Item as a cause of infertility ~ rat a well ~ Ed singe it is difficult to t=1 He infix ratio of lye into the "graft' is the basis or of F*
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From page 328... ...
His recognition may serve ~ gestate rekey ly~ki~ or g ~ fac Cars at the maternal interface. in this regard, a particularly exciting result f`=u cur laboratory has been the discovery that early embryos of domestic ungulates produce alpha-~nterferons in substantial quantities (47,49~.
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From page 329... ...
(56,57) have provided strong evidence that the variability ~ embryonic development seen at days 11 and 12 in Western breeds of pig is the result of late developing eggs giving rise to 1~== developed embryos.
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From page 330... ...
Referees So, R.V.
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From page 331... ...
1965. he influerx~e of maternal Trite con Reimplantation stages of pro in the ra}~it, ho.
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From page 332... ...
1986. Pleural piker s a decider protein that birds Stalin arm has an identical N-t~minal amino acid sauce with SO=t~; bird protein fun Oman amniotic fluid.
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From page 333... ...
1986. Repression specific vim carrier proteins involved In transplacenta~ vitamin Ardors In Is, incoming primate, I
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From page 334... ...
1988. Effect of electrocautery of Uvula day 1 follicles ~ ~t D=rpologi~1 variation day ll porcine Mayor.
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From page 335... ...
/; Hatches, elongates, ~ Replants (artbdacty~) (scab Breath reduced)
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