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Introduction
Pages 5-8

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From page 5...
... The progress of planning for effectiveness and related research throughout DHHS since 1988, and the movement of responsibility for effectiveness research into the Public Health Service as part of the Medical Treatment Effectiveness Program, makes clear that additional purposes for this program are important as well. Among these are improving patient outcomes, providing information useful in the development of practice guidelines, and identifying critical issues for further research.
From page 6...
... These conditions were given priority because they met several key selection criteria, including high prevalence, burden of the illness on elderly persons, appreciable variations in the use of services and in outcomes, high costs, and alternative ways to manage patient care that reflect professional and clinical disagreement or uncertainty. Apart from these points, the 1988 clinical workshop committee concluded that breast cancer takes on added importance because its incidence rises with age, which has special implications for morbidity and mortality as the elderly population grows and becomes predominantly female.
From page 7...
... Because including elderly women in efficacy studies and RCTs is likely to remain rare, and because quality of life looms very large for many women with breast cancer, the need for effectiveness studies becomes even more important. Research Workshop Committee For the research workshops, the IOM appointed a"core committee" of clinicians and researchers chaired by Kenneth I
From page 8...
... after reaching some consensus on the patient management issues for initial study, to suggest specific research strategies or approaches that might be implemented to address those issues. An underlying premise was the need to understand what aspects of the present or proposed Medicare databases might be used to accomplish the research, what should be added to the current databases, and what studies must be conducted independently of the HCFA databases.


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