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Technological Challenges in Antibiotic Discovery and Development A Workshop Summary (2014) / Chapter Skim
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5 General Observations
Pages 23-24

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From page 23...
... • There is not enough interaction among the dif- • Since the physiochemical properties of antimicro ferent constituencies that need to be involved in bial agents do not follow the same rules as other the discovery, development, and use of antibiot- classes of pharmaceutical agents, there is a need ics: between clinicians and researchers, between to develop synthetic and natural product libraries medicinal chemists and biologists, between small specifically for antibiotic development.
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Key Terms

  • microbial processes
  • novel screening
  • molecular structures
  • engineering secondary
  • novel molecular

  • companies developing
  • productive route
  • enter cells
  • develop novel
  • independent microbial

  • biophysical barriers
  • target independent
  • developing antibiotics
  • antibiotics enter
  • secondary metabolic

  • product libraries
  • medicinal chemists
  • antimicrobial agents
  • natural product
  • bypass biophysical

  • develop synthetic
  • microbial agents
  • antibiotic development
  • otic development
  • potential antibiotics

  • drug development
  • libraries medicinal
  • pharmaceutical agents
  • multiple targets
  • prior efforts


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