Nonhuman Primates Usage and Availability for Biomedical Programs (1975) / Chapter Skim
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Pages 3-10
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From page 3... ...
The overall administration of the proposed national plan should be undertaken by the National Institutes of Health (NIH) , with the advice of a committee representative of the national biomedical community.
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From page 4... ...
Hence, despite the possible application of artificial insemination, sperm banks, fertility drugs, or drugs that regulate reproductive cycles, there are no shortcuts or feasible alternatives to the development of large-scale breeding programs that depend on normal reproductive behavior. Indeed, even if fertility regulating techniques were to become feasible, it is likely that the costs would outweigh the potential benefits -- costs of trained staff, nurseries for hand-rearing multiple and premature infants, and technical work.
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From page 5... ...
Breeding in Countries of Origin Governmental actions in the countries from which primates of biomedical importance come indicate not only that animals for research and testing will become increasingly difficult to obtain in adequate numbers but that it maybe difficult in certain species, to obtain sufficient breeding stock to establish large-scale domestic production units. Despite the uncertainties, it is essential to support the establishment and operation of breeding colonies and production centers in countries of origin.
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From page 6... ...
Through various media -- periodic workshops, symposia, critical review articles -- the biomedical use of primates and other taxa should be reviewed, and primates replaced, whenever possible, by faster-breeding, more readily obtainable species. Where legislative or regulatory actions are proposed that would hamper ready access to suitable and easily bred nonprimate species (e.g.
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From page 7... ...
There should be provision primarily for colonies of outbred animals and also for production of inbred lines selected for specific physiologic and immunologic characteristics, where it has been demonstrated that primate models are essential. A number of activities and responsibilities are called for: • Review of proposals to breed primates.
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From page 8... ...
Computerized bibliographic services that might be expanded to incorporate information on available experimental material include Medline (National Library of Medicine-NLM) and Current Primate References (Washington Primate Center)
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From page 9... ...
• Working to minimize duplicative expeditions for trapping primates and assure priority assignment of females to breeding colonies, rather than to direct biomedical use. • Development of guidelines for trapping operations that take advantage of good wildlife management techniques, with a view to sustained yields from habitats that are to remain intact and animal salvage from habitats that are being destroyed.
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From page 10... ...
In other cases, specifications do not allow for acceptable alternative species or, conversely, unwittingly call for rare or endangered species where they are not in fact essential. For example, attention might well be directed to including acceptable alternate species such as Macaca fascicularis in the current federal requirement that presently permits the use of only rhesus macaques in neurovirulence testing for polio vaccines.
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