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A Framework to Guide Selection of Chemical Alternatives (2014) / Chapter Skim
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1 Introduction
Pages 9-16

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From page 9...
... "seek safer alternatives to harmful chemical For example, the CDC's Fourth National Report on ingredients in widely used products" (CA DTSC Human Exposure to Environmental Chemicals 2013a)
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From page 10...
... efforts, other countries have non-regulatory policies have been enacted that developed regulations that include the substitution require, conduct, or support the development of principle and require industry to transition to safer chemical alternatives assessments.
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From page 11...
... By making more chemical data, including information about exposure, hazard, and dose-response relationships, more easily GROWTH IN EVALUATIVE APPROACHES accessible through a variety of databases and dashboards, the EPA is improving the ability of Over the past decade, the number of interested parties to evaluate chemical substitutes. approaches for evaluating chemical toxicity has Having more institutions and companies complete grown substantially in response to many factors, chemical substitution assessments helps enhance the ranging from advances in molecular biology to public EPA's objective of ensuring safer chemistry.
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From page 12...
... . In these cases, manufacturers and reports that explored new approaches to assessing other parties select chemical alternatives to obtain chemical safety influenced the committee's the same or similar functionality.
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From page 13...
... Examples of applicable tools include limits in current life cycle assessment tools and could potentially lead to inaction. the freely available GreenScreen® for Safer Chemicals, which can be used for hazard screening, and SimaPro, which can be used for a This definition, with the addition of comparative evaluating life cycle impacts.
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From page 14...
... , exposure assessment, chemistry, committee's analysis of these reviews, a subset of and life cycle assessment. Additional expertise in existing frameworks were identified for more engineering, epidemiology, social sciences, detailed consideration; this selection was based on: economics, and cost analysis may also be (1)
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From page 15...
... Appendix D is a supplement other approaches. Chapters 7 and 8 address hazard to Chapter 8, providing additional information on assessment for ecotoxicity and human health, the United Nations Economic Commission for respectively.
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Key Terms

  • chemical alternatives
  • alternatives assessments
  • safer chemical
  • chemical substitution
  • chemical substitutions

  • green chemistry
  • chemical safety
  • safer chemicals
  • hazard assessment
  • regrettable substitutions

  • safer alternatives
  • chemical hazard
  • chemical design
  • cycle assessment
  • assessment policies

  • assessment tools
  • toxic chemicals
  • interstate chemicals
  • safer substitute
  • safer consumer

  • chemicals clearinghouse
  • unreasonable risk
  • toxic substances
  • available scientific
  • cycle impacts

  • toxicity testing
  • comparative exposure
  • data streams
  • develop consistent
  • efforts include


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