Multiple Chemical Sensitivities Addendum to Biologic Markers in Immunotoxicology (1992) / Chapter Skim
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Neurobehavioral and Psychosocial Aspects of Multiple Chemical Sensitivity
Neurobehavioral and Psychosocial Aspects of Multiple Chemical Sensitivity
Pages 109-116
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From page 109... ...
the exposures that elicit symptoms are very low, i.e. many standard deviations below the nTLV~ and at levels not Icoown to cause adverse human responses; 6)
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From page 110... ...
This consisted of a lifetime and current medical history, review of previous medical records, brief psychiatric history, physical examination, and routine hematology, blood chemistry, thyroid and urine studies. Further testing such as sp~rometry or chest x-ray were done as needed to document organic conditions whicl1 might reasonably explain the symptomatology.
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From page 111... ...
AD of the male patients worked With significant chemical or solvent exposures and first eypenenced symptoms In response to a change In ventilation or In a process at work, although none e~enenced a particular episode associated with accidental release or acute mto~ncation. The identified precipitating exposures and subsequent symptoms for five of the eight women occurred at work.
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From page 112... ...
Normative information for the tests cited above has taken into account differences In performance due to age and sew However, the normative information available generally does not take into account differences in performance due to general intellectual ability Therefore, a test of verbal ability is also administered as an estimate of overall intellectual ability. It Is generally assumed that basic verbal abilities such as vocabulary and weN-rehearsed general information win not be affected by acute or transient exposures to tome substances (Hartman, 19883.
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From page 113... ...
Psychiatric Assessment: Since many of the symptoms reported by MCS patients may also reflect psychological distress, several standard measures were selected to assess psychiatric symptomatology. The Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders - Third Edition - Revised (SCID-m-R - DSM-m-R)
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From page 114... ...
CONCLUSION A subset of MCS patients who meet more Ad criteria can be identified and characterized using standardized neurobebav~oral, psychiatric, and psychosocial measures of functioning. To make studies comparable, it Is important to develop standard selection cutena for patient selection and stan~rd~zed batteries for patient characterization.
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From page 115... ...
California Verbal Learning Test Manual. San Antonio: The Psychological Corporation; 1987.
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From page 116... ...
Acknowledgments This project was supported by a grant from the Hazardous Substance Management Research Center A National Science Foundation Indrus~y/ZJniversi~ Cooperative Center and A New Jersey Commission on Science and Technology Advanced Technology Center. We Ash to acknowledge the contributions of Kathie Kelly- McNeil and Carol Natarell`, who have both been instrumental a: providing die evaluation and care of our patients.
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