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Multiple Chemical Sensitivities Addendum to Biologic Markers in Immunotoxicology (1992) / Chapter Skim
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Exposures and Mechanisms
Pages 9-10

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From page 9...
... Therefore the following research approaches are suggested. HUMAN STUDIES Following a comprehensive history, including environmental exposures, physical examination and appropriate laboratory testing, subjects diagnosed with MCS and control individuals, should be challenged by exposure to a mixture of offending agents determined histoncaBy.
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From page 10...
... In addition, functional and morphological changes ~ cells and tissues should be evaluated using in vitro techniques. ADDITIONAL NEEDS Attempts should be made to develop a data base of chemical, foods and drugs, and associated signs and symptoms, which have been reported to be associated with MCS.
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Key Terms

  • physical examination
  • animal models
  • double blind
  • appropriate laboratory
  • subjects diagnosed

  • control individuals
  • human syndrome
  • lower concentrations
  • controlled procedure
  • blind controlled

  • laboratory testing
  • subsequent exposure
  • agents determined
  • research approaches
  • sensitivity caused

  • comprehensive history
  • polysymptomatic fashion
  • including environmental
  • associated signs
  • chemical exposures

  • environmental exposures
  • animal model
  • offending agents
  • objective evidence
  • chemical sensitivity

  • data base
  • include immunological
  • vitro techniques
  • include immunologic
  • following research


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