Biographical Memoirs Volume 61 (1992) / Chapter Skim
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John Holmes Dingle
John Holmes Dingle
Pages 136-163
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From page 137... ...
subsequent curriculum revision; anc! he served with distinction on numerous national advisory groups, most notably as director of the Commission on Acute Respiratory Diseases anc!
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Subsequently, again largely for financial reasons, he worker! as an assistant bacteriologist at the Maryland State Department of Health Laboratory and then joined the staff of Upjohn Company as a bacteriologist for two years before entering Harvard Medical School in 1935.
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pigeon as EKE virus, confirming the role of bircts in the transmission cycle. Concurrently, Dingle contributed his immunological expertise to studies with Thomas Hale Ham of a rare form of hemolytic anemia, paroxysmal nocturnal hemogIobinuria, and interested Ham in studying the coicl hemagglutinins associated with primary atypical pneumonia.
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Primary atypical pneumonia was recognized as an epidemic respiratory disease, perhaps an entity, distinct from then-known viral pneumonia, in the late 1930s. Finland.
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Among the major contributions to the development of knowledge of respiratory diseases in military personnel was the demonstration that at least three then uncultivatable filterable agents were responsible for three clinically and epidemiologically defined illnesses: atypical pneumonia, the common cold, and an influenza-like illness of recruits characterized at Fort Bragg and labeled acute respiratory disease (ARD)
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After-the war, the military deciclect that it still needled the advice of the Army Epiclemiological Board and the expertise of certain of its commissions. J Dingle, who was to continue as director of the Commission of Acute Respiratory Diseases until 1955, conceived the idea of applying its epiclemiological and laboratory methods to the study of civilian populations and sought an academic base at which to do so.
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With the approval of the Board of Trustees of the Academy of Medicine of Cleveland, whose then-president, Chauncey W Wyckoff, a pecliatrician, encouraged participation by his patients, Dingle's staff eventually recruited eighty-six families, with 443 individuals, resident in middle-class suburbs within easy driving distance of the medical school to participate in what became known as the Cleveland Family Study.
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Hale Ham was recruitect to conduct this "experiment in medical education," and his frienc! and colleague Dingle became an active participant in the key committees and planning sessions that evolvecI.
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knowledge of infectious diseases and a concern for expanded basic and clinical research both at home and abroad. This group incluclec!
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V Brown, a native of nearby Fayetteville, while she was working as a secretary for the Commission on Acute Respiratory Diseases.
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He was a member of the advisory boards of the Cleveland Health Department, the Maternal Health Association, and the Cleveland Diabetic Fund. He was an active member of the National Research Council's Subcommittee on Infectious Diseases and its successor, the Subcommittee on Infectious Diseases and Chemotherapy, for ten years, serving as chairman in 1950-53.
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The practical importance of enzymic inactivation by preliminary scalding of peas intended for frozen pack. Food Industries (August)
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A fatal disease of pigeons caused by the virus of the eastern variety of equine encephalomyelitis. Science 88:54950.
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II. Chronic hemolytic anemia with paroxysmal nocturnal hemoglobinuria: Certain immunological aspects of the hemolytic mechanism with special reference to serum complement.
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II. Primary atypical pneumonias of unknown etiology.
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With the Commission on Acute Respiratory Diseases. Primary atypical pneumonia.
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77:143-210. With the Commission on Acute Respiratory Diseases and the New York State Department of Health.
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25:347-51. With the Commission on Acute Respiratory Diseases.
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II. Immunity on reinoculation with agents from two types of minor respiratory illness and from primary atypical pneumonia.
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With the Commission on Acute Respiratory Diseases. Clinical patterns of undifferentiated and other acute respiratory diseases in army recruits.
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The failure of antihistaminic drugs to prevent or cure the common cold and undifferentiated respiratory diseases.
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II. Incidence of the common respiratory diseases.
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VIII. Relation of tonsillectomy to incidence of common respiratory diseases in children.
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Outbreak of unusual form of pneumonia at Camp Gruber, Oklahoma, in 1944. Follow-up studies implicating Histoplasma capsulatum as etiologic agent.
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An approach to evaluation of medical education at Western Reserve University.
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Fluorescent-stainable antibodies to the Eaton agent in human primary atypical pneumonia transmission studies.
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Illness in the Home: A Study of 25,000 mnesses in a Group of Cleveland Families. Cleveland: Western Reserve University Press.
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