BioWatch PCR Assays Building Confidence, Ensuring Reliability: Abbreviated Version (2015) / Chapter Skim
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Appendix C: Glossary
Appendix C: Glossary
Pages 167-170
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From page 167... ...
that causes disease in humans, plants, or animals and is used in bio terrorism or biological warfare. Biosurveillance: The process of active data-gathering with appropriate analysis and interpretation of biosphere data that might relate to disease activity and threats to human or animal health -- whether infectious, toxic, metabolic, or otherwise, and regardless of inten tional or natural origin -- in order to achieve early warning of health threats, early detection of health events, and overall situational awareness of disease activity.
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From page 168... ...
Environmental sampling: In the context of the BioWatch system, physi cal sampling of the environment around a collector associated with a positive PCR assay result to provide decision makers with additional situational assessment and to inform appropriate response actions. Environmental surveillance: Monitoring of the environment to evalu ate potential exposure to harmful agents and damage to living organisms.
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From page 169... ...
Multiplex (PCR assay) : A type of PCR assay designed to simultane ously amplify and detect multiple target regions of nucleic acid in a single sample.
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From page 170... ...
Threshold cycle (Ct) : In the context of a real-time PCR assay, the cycle number at which the amplification curve crosses a specified thresh old level, indicating that amplification of the target region is above a background level.
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