International Summit on Human Gene Editing A Global Discussion (2015) / Chapter Skim
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International Summit on Human Gene Editing A Global Discussion
International Summit on Human Gene Editing A Global Discussion
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advance biological understanding, alter the A new technique using a molecular assemblage genomes of microbes, plants, and animals, and known as CRISPR-Cas9, which arose out of treat human diseases. They also have raised research into how bacteria protect themselves profound questions about how people may from viral infection, is simple, inexpensive, and choose to alter not only their own DNA but the can target DNA sequences with great specificity.
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It is being used to study human germ cells, which include sperm cells, the differentiation of human sperm and egg egg cells, and the progenitors of those cells. cells, fertilization, cell division, and embryonic Germline gene editing also could be done in development.
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"Before prospective partners, the use of sperm or egg we make permanent changes to the human gene donors, prenatal diagnosis and termination of a pool, we should exercise considerable caution." pregnancy, and adoption. Patients with genetic diseases have a strong Many genetic diseases are not amenable to drive to find cures for those diseases, noted germ cell gene editing, including those caused by George Daley (Boston Children's Hospital)
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Benjamin and Bliss both noted the human gene editing until an international ban on importance of including diverse perspectives germline gene editing for reproductive purposes so that assessments of risks and benefits are not can be secured through the United Nations limited to medical risks alone. and regional bodies can prepare internationally The prospect of human gene editing binding regulations.
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By abolishing the separation of science and technology from public discussion and governance, it represents a fundamental transformation of the innovation system. "It Photo of meeting participants left to right: George Daley, could lead to a shared responsibility of all Jennifer Doudna, and David Baltimore relevant stakeholders on the key issues and on the Source: Pam Risdom governance of human gene editing," Reiss said.
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"This summit human embryos or germline cells undergo gene will not be the last word on human gene editing," editing, the modified cells should not be used to concluded organizing committee chair David establish a pregnancy. Baltimore.
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The international community should strive to establish norms concerning Organizing Committee for the International Summit acceptable uses of human germline editing and on Human Gene Editing: David Baltimore (chair) , to harmonize regulations, in order to discourage California Institute of Technology; Françoise Baylis, unacceptable activities while advancing human Dalhousie University; Paul Berg, Stanford University health and welfare.
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National Academy of Sciences, the U.S. National Academy of Medicine, the Royal Society, or the Chinese Academy of Sciences.
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