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1 INTRODUCTION
Pages 15-18

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From page 15...
... Objectionable dental fluorosis is a mottling of dental enamel characterized by staining or pitting. In addition to ingesting fluoride in drinking water, people now receive fluoride from a large number of other sources, such as toothpastes, mouth rinses, soft drinks, tea, processed foods, and vegetables.
From page 16...
... Assertions have been made that fluoride is related to skeletal fluorosis and subsequent fractures, cancer, soiPt-tissue effects, and arthritis. Critical analysis of toxicological data on fluoride has shown, however, that important adverse health effects, such as crippling skeletal fluorosis and kidney ant} other softtissue damage, occur in humans only when fluoride concentrations in drinking water exceed ~ mg/L for many years.
From page 17...
... This report is the result of a detailed evaluation of possible adverse health effects associated with ingested fluoride. The report examines in detail the current data on carcinogenicity of fluoride in humans and animals, dental fluorosis, skeletal effects, effects on the renal, gastrointestinal, and immune systems, effects on reproduction, ant]


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