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The Children's Vaccine Initiative Achieving the Vision (1993) / Chapter Skim
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Appendix H: Historical Record of Vaccine Product License Holders in the United States
Pages 196-204

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From page 196...
... H Historical Record of Vaccine Product :License Holders in the United States TABLE H-1 Vaccine Product License Holders in the United States Company and Vaccine or Product Date of Date of License Revocation Bionetics Research Inc.a BCG vaccine 05/29/1987 06/21/1989 Connaught Laboratories, Inc.b BCG live 05/21/1990 BCG vaccine 03/31/1967 05/21/1990 Diphtheria & tetanus toxoids & acellular pertussis vaccine, adsorbed 09/20/1992 Diphtheria & tetanus toxoids & pertussis vaccine (DEEP) 01/03/1978 11/29/1982 Diphtheria & tetanus toxoids, & pertussis vaccine, adsorbed 01/03/1978 Diphtheria & tetanus toxoids adsorbed 09/18/1984 Diphtheria toxoid 01/03/1978 Haemophilus influence type b Conjugate (diphtheria toxoid conjugate)
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From page 197...
... Yellow fever Connaught Laboratories, Limitedb Diphtheria toxoid Tetanus toxoid Small pox vaccine 12/20/1985 01/03/1978 01/03/1978 01/03/1978 01/03/1978 11/23/1981 01/03/1978 11/20/1987 01/24/1963 12/27/1991 01/03/1978 01/03/1978 01/03/1978 01/03/1978 01/03/1978 04/28/1928 05/27/1977 01/14/1943 10/23/1967 04/01/1980 Dow Chemical Companya Diphtheria & tetanus toxoids & pertussis vaccine adsorbed 09/11/1970 06/07/1977 Diphtheria toxoid 09/18/1934 06/07/1977 DT, adsorbed 09/11/1970 06/07/1977 DP, adsorbed 09/11/1970 06/07/1977 Measles, live 02/05/1965 06/07/1978 Measles and rubella, live 04/17/1974 06/21/1978 Measles, mumps, rubella, live 04/17/1974 06/21/1978 Mumps virus vaccine, live 04/17/1974 06/21/1978 Pertussis vaccine 10/01/1932 06/07/1977 Rubella virus, live 03/01/1974 06/21/1978 Tetanus toxoid 08/01/1936 06/07/1977 Tetanus toxoid, adsorbed 09/01/1970 06/07/1977 Eli Lilly and Companya Cholera 10/31/1917 06/07/1979 Diphtheria & tetanus toxoids 09/09/1970 06/07/1979 Continues
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From page 198...
... 198 TABLE H-1 Continued APPENDIX H Company and Vaccine or Product Date of Date of License Revocation Diphtheria & tetanus toxoids and pertussis vaccine adsorbed 09/09/1970 12/02/1985 DT, adsorbed 09/09/1970 06/07/1979 Influenza 11/09/1945 04/11/1977 Mumps vaccine 01/27/1950 04/11/1977 Pertussis vaccine 03/31/1915 03/07/1978 Rabies vaccine 06/07/1915 08/11/1982 Streptococcus vaccine 04/17/1952 10/27/1988 Tetanus toxoid 12/10/1935 06/07/1979 Tetanus toxoid, adsorbed 09/09/1970 06/07/1979 Tetanus & diphtheria toxoid adsorbed (for adult use) 09/09/1970 06/07/1979 Typhoid 02/04/1954 11/13/1978 Typhus 03/11/1941 06/07/1979 Evans Medical Ltd.C Influenza 08/12/1988 Glaxo Operations, U.K Ltd.a BCG vaccine 01/24/1963 07/17/1990 Lederle Laboratories,d American Cyanamid Company Cholera 12/26/1941 Diphtheria & tetanus toxoids and acellular pertussis, adsorbed 12/17/1991 Diphtheria & tetanus toxoids and pertussis vaccine adsorbed 07n4/1970 DT, adsorbed 07/29/1970 Haemophilu~ influenzas type b 12/20/1985 polysaccharide vaccine Influenza 12/07/1945 Measles virus, live 05/03/1966 05/21/1980 Mumps vaccine 06/22/1950 05/24/1978 Pertussis vaccine 01/19/1914 05/29/1980 Pneumococcal vaccine, polyvalent 08/15/1979 Polio virus, live, oral trivalent 06/2S/1963 Polio virus, oral, type 1 03/27/1962 Polio virus, oral, type 2 03/27/1962 Polio virus, oral, type 3 03n7/1962 Rocly mountain spotted fever 04/13/1942 06/11/1979 Small pox 03/01/1937 05/24/1978 Tetanus toxoid 06/15/1935 Tetanus toxoid, adsorbed 07/29/1970
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From page 199...
... Typhoid Merck and Company Cholera Diphthena & tetanus toxoids and pertussis vaccine adsorbed Haemophilus inpuenzoe type b conjugate (meningococcal protein conjugate) Hepatitis B vaccine Hepatitis B recombinant Influenza Measles, live and small pox Measles virus, live Measles and mumps virus, live Measles and rubella virus, live Measles, mumps, rubella, live Meningococcal polysacchande A Meningococcal polysacchande C Meningococcal polysacchande A&C hleningococcal polycsacchande A, C, Y
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From page 200...
... 03/07/1955 01/03/1978 Yellow fever 05/22/1953 01/03/1978 Michigan Department of Public Health Anthrax 11/04/1970 Diphtheria & tetanus toxoids and Pertussis vaccine adsorbed 08/27/1970 DT, adsorbed 08/27/1970 Pertussis vaccine 11/22/1935 02/03/1977 Pertussis vaccine, adsorbed 10/12/1967 Rabies vaccine, adsorbed 03/18/1988 Smallpox 03/03/1937 06/25/1985 Tetanus toxoid, adsorbed 08/27/1970 Typhoid 07/26/1926 06/25/1985 Miles Inc.e Cholera 10/03/1968 10/30/1970 Diphtheria and tetanus toxoids 06/01/1951 10/30/1970 DTP 05/04/1949 10/30/1970 Diphtheria & tetanus toxoids 05/04/1949 10/30/1970 and Pertussis vaccine adsorbed Diphtheria toxoid 02/01/1928 10/30/1970 DT, adsorbed 05/04/1949 10/30/1970 DP, adsorbed 05/04/1949 10/30/1970
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From page 201...
... 11/16/1956 10/30/1970 Typhoid 03/06/1916 10/30/1970 Organon Tel;nika Corporatione BCG vaccine 06/21/1989 Parke Davis, Division of Warner Lambert Companya Adenovirus 09/23/1957 07/29/1980 Adenovirus and influenza, combined aluminun phosphate adsorbed 09/22/1959 07/29/1980 Diphtheria and tetanus toxoids 07/29/1952 10/14/1981 DTP 07/29/1952 10/14/1981 Diphtheria & tetanus toxoids & Pertussis 07tO8/1952 10/14/1981 vaccine adsorbed Diphtheria toxoid 08/17/1927 10/14/1981 DT, adsorbed 07/08/1952 10/14/1981 DTP adsorbed, poliomyelitis 12/20/1963 10/14/1981 DTP, poliomyelitis adsorbed 03/25/1959 10/14/1981 Influenza 11/26/1945 Pertussis 04/16/1952 10/14/1981 Pertussis vaccine, adsorbed 02/20/1952 10/14/1981 Poliomyelitis, adsorbed 10/04/1960 07/29/1980 Poliomyelitis, inactivated monkey kidney cell 04/12/1955 07/29/1980 Rabies vaccine 08/05/1942 03/21/1973 Tetanus toxoid 05/04/1940 10/14/1981 Tetanus toxoid, adsorbed 07/08/1952 10/14/1981 Typhoid 03/24/1916 02/24/1959 Typhus 03/25/1942 08/05/1947 Pasteur Merieux Vaccins et Serums, S Nb Poliomyelitis, inactivated monkey kidney cell Rabies vaccine 12/21/1990 06/09/1980 Continues
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From page 202...
... SmithKline Beechan~e Hepatitis B recombinant Rubella virus, live Swiss Serum Institute Tetanus toxoid, adsorbed Typhoid vaccine, oral, Ty21a Takeda Chemical Industries, Ltd., 08/20/1992 12/10/1992 08/19/1976 03/31/1978 01/04/1963 03/31/1978 01/04/1963 08/05/1970 02/16/1979 08/28/1989 03/12/1970 12/11/1970 12/15/1989 10/05/1982 Acellular pertussis vaccine concentrate (for further manufacturing)
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From page 203...
... ; Medeva International pie acquired the vaccine business from Wellcome in 1991. d Lederle Laboratories acquired Praxis Biologics in 1989.
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Key Terms

  • pertussis vaccine
  • vaccine adsorbed
  • acellular pertussis
  • diphtheria toxoid
  • kidney cell

  • rabies vaccine
  • vaccine concentrate
  • monkey kidney
  • tetanus toxoid
  • medeva international

  • inactivated monkey
  • virus vaccine
  • lederle laboratories
  • rubella virus
  • cell rabies

  • mumps virus
  • laboratories acquired
  • praxis biologics
  • toxoid tetanus
  • meningococcal protein

  • vaccine business
  • bcg vaccine
  • protein conjugate
  • acquired praxis
  • connaught laboratories

  • measles virus
  • yellow fever
  • public health
  • company cholera
  • american cyanamid


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