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Review of Report and Approach to Evaluating Long-Term Health Effects in Army Test Subjects:
Pages 1-6

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From page 1...
... The potential long-term health effects on the test subjects from their exposures have been evaluated periodically, most recently in a report titled Assessment of Potential Long-Term Health Effects on Army Human Test Subjects of Relevant Biological and Chemical Agents, Drugs, Medications and Substances: Literature Review and Analysis (the Report) , which was prepared by a contractor (Ho-Chunk Technical Solutions 2016)
From page 2...
... The committee finds that the Report should not be used as the sole scientific basis to assess the potential long-term health effects from exposure to biological and chemical agents, drugs, medications, and substances. The committee recommends that the Army develop a streamlined, scientifically rigorous approach to categorize health hazards and, given the number of agents to be reviewed, a strategy to prioritize the evaluations.
From page 3...
... Therefore, the committee questions whether the IOM Vaccine Approach, beyond the categories of causality conclusions, is the most suitable for the Army's purposes. It is likely that animal and mechanistic data will be important in hazard evaluations for many test agents and substances; therefore, other weight-of-evidence frameworks, such as those from IOM (1994, 2000, 2016)
From page 4...
... NOTE: ACGIH = American Conference of Governmental Industrial Hygienists; ATSDR = Agency for Toxic Substances and Disease Registry; EPA = U.S. Environmental Protection Agency; IARC = International Agency for Research on Cancer; ID = identification; IOM = Institute of Medicine; National Academies = National Academies of Sciences, Engineering, and Medicine; NTP = National Toxicology Program.
From page 5...
... 2009b. Military chemical warfare agent human subjects testing: Part 2 – Long-term health effects among participants of U.S.
From page 6...
... Process. Washington, DC: The National Academies Press.


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