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2 Exploring Opportunities Afforded by Mobile Technology
Pages 5-8

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From page 5...
... For example, neurologists typically assess gait by observing their patients as they walk down a corridor. Digital technologies can provide complementary information about function and context by capturing more quantitative measures of gait parameters as well as other real-world parameters related to walking, such as destination and frequency of walking to a destination, said Marks.
From page 6...
... , he said, but they have broadened into the digital biomarker field when they saw their potential of wearable devices to be used as clinical research endpoints and realized that many of the issues faced in developing digital biomarkers are similar to those encountered in imaging 5 to 10 years ago. He predicted that while digital biomarkers may eventually supplant some rating scales and other subjective measures of function, it may be more likely that they will provide complementary quantitative input to those scales.
From page 7...
... For neuropsychiatric disorders that are highly recurrent, such as bipolar disorder, digital technologies may also provide early warning signals of an impending cycle, switch to mania, or suicidal intent, he said. Because these recurrences and relapses may contribute to the pathogenesis of disease, Manji suggested that detecting early warning signs and intervening at that point could potentially impact disease progression (Narayan and Manji, 2016)
From page 8...
... Moreover, a regulatory path for using digital data has yet to be developed, said Onnela, noting that data privacy and security remain substantial concerns for consumers, device developers, and regulators alike (Chapters 4 and 6)


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