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Toxicity Testing Strategies to Determine Needs and Priorities (1984) / Chapter Skim
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6. CONCLUSIONS AND RECOMMENDATIONS
Pages 295-296

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From page 295...
... Such analytic techniques as systems analysis and decision theory appear to permit design approaches with those characteristics. Application of these analytic techniques requires, however, that each information-gathering or testing procedure be described quantitatively with respect to its ability to identify potentially toxic chemicals; and the current art of toxicity testing and priority-setting does not readily permit such quantitative descriptions with great precision.
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From page 296...
... In the light of that impediment, the following may be considered as characteristics of a system that would advance the state of the art of priority-setting: · Use of explicit, detailed, and formal decision-making procedures in selecting and ranking chemicals for testing, such as are illustrated in the approach described in this report, which is based on principles of systems analysis and decision theory. · Validation and quantification of the performance characteristics of all tests and other information-gathering procedures used in the testing programe · Development of relevant data bases, including those related to the production and use of chemicals, to the potential for human exposure, to structure-activity relationships, and to toxic activity.
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Key Terms

  • testing procedures
  • potential toxicity
  • analytic techniques
  • decision theory
  • toxic chemicals

  • permit design
  • current art
  • systematic screening
  • potentially toxic
  • toxic activity

  • perceived relative
  • identify potentially
  • testing resources
  • testing procedure
  • potential health

  • set priorities
  • approach described
  • ranking chemicals
  • nominating substances
  • entire select

  • toxicity testing
  • readily permit
  • relevant data
  • described quantitatively
  • techniques requires

  • selection procedures
  • quantitative descriptions
  • theory appear
  • toxicity information
  • various toxicity


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